Correction of nonuniform attenuation in cardiac SPECT imaging

Benjamin Tsui, G. T. Gullberg, E. R. Edgerton, J. G. Ballard, J. R. Perry, W. H. McCartney, J. Berg

Research output: Contribution to journalArticle

Abstract

Correction for photon attenuation in cardiac SPECT imaging using a measured attenuation distribution with an iterative expectation maximization (EM) algorithm and an iterative Chang algorithm were compared with the conventional filtered backprojection and an iterative EM algorithm without attenuation correction. The attenuation distribution was determined from a transmission computed tomography study that was obtained using an external collimated sheet source. The attenuation of the emitting photons was modeled in the EM algorithm by an attenuated projector-backprojector that used the estimated attenuation distribution to calculate attenuation factors for each pixel along each projection and backprojection ray. Results from a heart-lung phantom study and a 201Tl patient study demonstrated that the iterative EM algorithm with attenuation correction provided improved image quality in terms of reduced streak artifacts and noise, and more accurate quantitative information in terms of improved radioactivity distribution uniformity where uniformity existed, and better anatomic object definition.

Original languageEnglish (US)
Pages (from-to)497-507
Number of pages11
JournalJournal of Nuclear Medicine
Volume30
Issue number4
StatePublished - 1989
Externally publishedYes

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Single-Photon Emission-Computed Tomography
Photons
X Ray Computed Tomography
Artifacts
Radioactivity
Noise
Lung

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Tsui, B., Gullberg, G. T., Edgerton, E. R., Ballard, J. G., Perry, J. R., McCartney, W. H., & Berg, J. (1989). Correction of nonuniform attenuation in cardiac SPECT imaging. Journal of Nuclear Medicine, 30(4), 497-507.

Correction of nonuniform attenuation in cardiac SPECT imaging. / Tsui, Benjamin; Gullberg, G. T.; Edgerton, E. R.; Ballard, J. G.; Perry, J. R.; McCartney, W. H.; Berg, J.

In: Journal of Nuclear Medicine, Vol. 30, No. 4, 1989, p. 497-507.

Research output: Contribution to journalArticle

Tsui, B, Gullberg, GT, Edgerton, ER, Ballard, JG, Perry, JR, McCartney, WH & Berg, J 1989, 'Correction of nonuniform attenuation in cardiac SPECT imaging', Journal of Nuclear Medicine, vol. 30, no. 4, pp. 497-507.
Tsui B, Gullberg GT, Edgerton ER, Ballard JG, Perry JR, McCartney WH et al. Correction of nonuniform attenuation in cardiac SPECT imaging. Journal of Nuclear Medicine. 1989;30(4):497-507.
Tsui, Benjamin ; Gullberg, G. T. ; Edgerton, E. R. ; Ballard, J. G. ; Perry, J. R. ; McCartney, W. H. ; Berg, J. / Correction of nonuniform attenuation in cardiac SPECT imaging. In: Journal of Nuclear Medicine. 1989 ; Vol. 30, No. 4. pp. 497-507.
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