Corneal wound healing: holographic stress-test analysis

J. L. Calkins, B. F. Hochheimer, W. J. Stark

Research output: Contribution to journalArticle

Abstract

Double-exposure holograms are taken of the patient's cornea after a heartbeat. The resulting stress test, or holographic interferogram, shows sharply demarcated fringe patterns outlining structurally weak areas in the cornea. Wound strength in postoperative keratoplasties is now being evaluated on a routine basis to determine the effect of topical modifications and surgical techniques. All grafts measured to date reveal 'bulging' or weakness of the wound margin by holography even though clinically they are fully 'healed'. Only one patient had a vascularized region of the wound that was stronger than surrounding cornea. It is no longer necessary to resort to pulling the wound apart in animals for measurement of tensile strength.

Original languageEnglish (US)
Pages (from-to)322-334
Number of pages13
JournalInvestigative Ophthalmology and Visual Science
Volume21
Issue number2
StatePublished - 1981

Fingerprint

Exercise Test
Wound Healing
Cornea
Wounds and Injuries
Holography
Corneal Transplantation
Tensile Strength
Transplants

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Calkins, J. L., Hochheimer, B. F., & Stark, W. J. (1981). Corneal wound healing: holographic stress-test analysis. Investigative Ophthalmology and Visual Science, 21(2), 322-334.

Corneal wound healing : holographic stress-test analysis. / Calkins, J. L.; Hochheimer, B. F.; Stark, W. J.

In: Investigative Ophthalmology and Visual Science, Vol. 21, No. 2, 1981, p. 322-334.

Research output: Contribution to journalArticle

Calkins, JL, Hochheimer, BF & Stark, WJ 1981, 'Corneal wound healing: holographic stress-test analysis', Investigative Ophthalmology and Visual Science, vol. 21, no. 2, pp. 322-334.
Calkins, J. L. ; Hochheimer, B. F. ; Stark, W. J. / Corneal wound healing : holographic stress-test analysis. In: Investigative Ophthalmology and Visual Science. 1981 ; Vol. 21, No. 2. pp. 322-334.
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