Corneal ulceration, measles, and childhood blindness in Tanzania

A. Foster, A. Sommer

Research output: Contribution to journalArticlepeer-review

Abstract

One hundred and thirty Tanzanian children with corneal ulceration were clinically examined to determine the cause of the ulceration. 37% of the ulcers were associated with recent measles infection and 38% of the children had bilateral ulceration. Herpes simplex virus infection was the commonest cause of ulceration in the series, but vitamin A deficiency was the major cause of bilateral ulceration, subsequent blindness, and mortality in this series. Other significant causes of childhood corneal ulceration were the use of traditional eye medicines, confluent measles keratitis, and ophthalmia neonatorum. We discuss the various mechanisms by which measles causes corneal ulceration, and the priorities in prevention and management of corneal ulceration in African children.

Original languageEnglish (US)
Pages (from-to)331-343
Number of pages13
JournalBritish Journal of Ophthalmology
Volume71
Issue number5
DOIs
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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