Abstract
Purpose: To describe a case of corneal ulceration associated with dupilumab use for atopic dermatitis. Observations: A patient developed an inflammatory corneal ulcer 3 weeks after starting bi-weekly intravenous dupilumab therapy. Symptoms resolved with topical prednisolone and discontinuation of the systemic therapy with dupilumab. Conclusion and importance: Dupilumab is known to cause ocular surface inflammation, but we report a novel association between dupilumab use and potentially sight-threatening corneal ulceration.
Original language | English (US) |
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Article number | 100848 |
Journal | American Journal of Ophthalmology Case Reports |
Volume | 19 |
DOIs | |
State | Published - Sep 2020 |
Keywords
- Atopic dermatitis
- Conjunctivitis
- Corneal ulceration
- Dupilumab
ASJC Scopus subject areas
- Ophthalmology