Corneal perforations. Changing methods of treatment, 1960-1980

L. W. Hirst, W. E. Smiddy, W. J. Stark

Research output: Contribution to journalArticle

Abstract

One hundred four nontraumatic corneal perforations or descemetoceles in patients admitted to the Wilmer Institute from 1960 to 1980 were studied retrospectively, with follow-up data obtained from records or from referral physicians for 87 of these perforations. Forty-nine percent of the cases were caused by bacterial corneal ulcers, 13% by exposure, 12% by chemical burns, 6% by fungal keratitis, 5% by herpes simplex keratitis, and 15% were undiagnosed. Since the start of tissue adhesive use at the Wilmer Institute in 1974, there has been an apparent trend towards a lower enucleation rate (6%) in corneal perforations treated with tissue adhesive as compared to 19% in perforations treated by other therapies, although the cases may not be entirely comparable. An improved visual result of 20/200 or better was achieved in 29% of patients treated with tissue adhesive as compared to 19% with other treatments.

Original languageEnglish (US)
Pages (from-to)630-635
Number of pages6
JournalOphthalmology
Volume89
Issue number6
StatePublished - 1982

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Corneal Perforation
Tissue Adhesives
Chemical Burns
Herpetic Keratitis
Corneal Ulcer
Keratitis
Therapeutics
Referral and Consultation
Physicians

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Hirst, L. W., Smiddy, W. E., & Stark, W. J. (1982). Corneal perforations. Changing methods of treatment, 1960-1980. Ophthalmology, 89(6), 630-635.

Corneal perforations. Changing methods of treatment, 1960-1980. / Hirst, L. W.; Smiddy, W. E.; Stark, W. J.

In: Ophthalmology, Vol. 89, No. 6, 1982, p. 630-635.

Research output: Contribution to journalArticle

Hirst, LW, Smiddy, WE & Stark, WJ 1982, 'Corneal perforations. Changing methods of treatment, 1960-1980', Ophthalmology, vol. 89, no. 6, pp. 630-635.
Hirst LW, Smiddy WE, Stark WJ. Corneal perforations. Changing methods of treatment, 1960-1980. Ophthalmology. 1982;89(6):630-635.
Hirst, L. W. ; Smiddy, W. E. ; Stark, W. J. / Corneal perforations. Changing methods of treatment, 1960-1980. In: Ophthalmology. 1982 ; Vol. 89, No. 6. pp. 630-635.
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