Corneal endothelial cytotoxicity of the calotropis procera (ushaar) plant

Hani S. Al-Mezaine, Mohammed A. Al-Amry, Abdullah Al-Assiri, Talal S. Fadel, Khalid F. Tabbara, Ali A. Al-Rajhi

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To report 6 eyes of 5 patients with transient corneal edema after exposure to the milky latex of Calotropis procera (ushaar). METHODS: Interventional case series. RESULTS: Intracorneal penetration of ushaar latex can lead to permanent endothelial cell loss with morphologic alteration. Corneal edema resolved completely in ∼2 weeks in all cases, despite reduced endothelial cell count and abnormal morphology. CONCLUSIONS: Corneal endothelial toxicity of ushaar latex is caused by its ability to penetrate the corneal stroma and induce permanent loss of endothelial cells. Corneal edema resolves if sufficient endothelial cell viability is still present after resolution of ushaar keratitis.

Original languageEnglish (US)
Pages (from-to)504-506
Number of pages3
JournalCornea
Volume27
Issue number4
DOIs
StatePublished - May 2008
Externally publishedYes

Keywords

  • Calotropis procera
  • Corneal edema
  • Corneal endothelium
  • Corneal toxicity
  • Milkweed
  • Ushaar

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Corneal endothelial cytotoxicity of the calotropis procera (ushaar) plant'. Together they form a unique fingerprint.

Cite this