Corneal decompensation in mitochondrial ophthalmoplegia plus (Kearns- Sayre) syndrome: A clinicopathologic case report

T. S. Chang, D. R. Johns, W. J. Stark, D. B. Drachman, W. R. Green

Research output: Contribution to journalArticlepeer-review

Abstract

The authors describe the clinical, molecular genetic, and pathologic findings of a patient with corneal decompensation associated with the mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. Ultrastructurally abnormal mitochondria were observed and possibly implicate this organelle in the pathogenesis of corneal edema.

Original languageEnglish (US)
Pages (from-to)269-273
Number of pages5
JournalCornea
Volume13
Issue number3
DOIs
StatePublished - Jan 1 1994

Keywords

  • Clinicopathologic correlation
  • Corneal decompensation
  • Electron microscopy
  • Kearns-Sayre syndrome
  • Mitochondria
  • Mitochondrial encephalomyopathy
  • Ophthalmoplegia plus
  • Progressive external ophthalmoplegia

ASJC Scopus subject areas

  • Ophthalmology

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