Cord blood stem cell banking and transplantation

J. W. Adamson, [No Value] Spangrube, B. Torok-Storb, H. E. Broxmeyer, [No Value] Griffin, P. J. Quesenberry, W. E. Fibbe, L. Kanz, S. J. Sharkis, R. Hoffman, T. Papayannopoulou

Research output: Contribution to journalArticle

Abstract

Cord blood banking for the purpose of stem cell transplantation is a rapidly growing area of medical interest. Based on the fact that cord blood contains large numbers of stem and progenitor cells, transplantation of cord blood for marrow reconstitution was first attempted in 1988. The success of this initial transplant between related donor and patient rapidly led to the establishment of efforts to collect, store and eventually transplant unrelated cord blood samples. A collection and storage program established by the New York Blood Center has led to more than 400 such transplants. The results demonstrate acceptable rates of engraftment and little graft-versus- host disease compared to the results employing adult marrow. As a consequence of these observations, considerable effort is being made to establish cord blood banks around the world.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalStem Cells
Volume15
Issue numberSUPPL. 1
StatePublished - 1997
Externally publishedYes

Fingerprint

Cord Blood Stem Cell Transplantation
Fetal Blood
Blood Banks
Stem Cell Transplantation
Transplants
Bone Marrow
Graft vs Host Disease
Stem Cells
Tissue Donors

Keywords

  • Cell dose threshold
  • Cord blood
  • Cord blood banking
  • Cord blood stem cell biology
  • Cord blood transplantation
  • Graft-versus-host disease
  • Graft-versus-leukemia effect
  • Stem cells

ASJC Scopus subject areas

  • Cell Biology

Cite this

Adamson, J. W., Spangrube, N. V., Torok-Storb, B., Broxmeyer, H. E., Griffin, N. V., Quesenberry, P. J., ... Papayannopoulou, T. (1997). Cord blood stem cell banking and transplantation. Stem Cells, 15(SUPPL. 1), 57-61.

Cord blood stem cell banking and transplantation. / Adamson, J. W.; Spangrube, [No Value]; Torok-Storb, B.; Broxmeyer, H. E.; Griffin, [No Value]; Quesenberry, P. J.; Fibbe, W. E.; Kanz, L.; Sharkis, S. J.; Hoffman, R.; Papayannopoulou, T.

In: Stem Cells, Vol. 15, No. SUPPL. 1, 1997, p. 57-61.

Research output: Contribution to journalArticle

Adamson, JW, Spangrube, NV, Torok-Storb, B, Broxmeyer, HE, Griffin, NV, Quesenberry, PJ, Fibbe, WE, Kanz, L, Sharkis, SJ, Hoffman, R & Papayannopoulou, T 1997, 'Cord blood stem cell banking and transplantation', Stem Cells, vol. 15, no. SUPPL. 1, pp. 57-61.
Adamson JW, Spangrube NV, Torok-Storb B, Broxmeyer HE, Griffin NV, Quesenberry PJ et al. Cord blood stem cell banking and transplantation. Stem Cells. 1997;15(SUPPL. 1):57-61.
Adamson, J. W. ; Spangrube, [No Value] ; Torok-Storb, B. ; Broxmeyer, H. E. ; Griffin, [No Value] ; Quesenberry, P. J. ; Fibbe, W. E. ; Kanz, L. ; Sharkis, S. J. ; Hoffman, R. ; Papayannopoulou, T. / Cord blood stem cell banking and transplantation. In: Stem Cells. 1997 ; Vol. 15, No. SUPPL. 1. pp. 57-61.
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