Conversion of FDG PET activity of fibrous dysplasia of the skull late in life mimicking metastatic disease

David Bonekamp, Heather Jacene, Detlef Bartelt, Nafi Aygun

Research output: Contribution to journalArticle

Abstract

Fibrous dysplasia (FD) accounts for 7% of benign bone tumors. It is a developmental disorder of unclear etiology. The lamellar cancellous bone of the medullary cavity is replaced with immature fibroosseous tissue. We describe a case of FD of the skull in a patient of advanced age (69 years) with recent diagnosis of colon cancer, which changed its FDG activity and CT appearance within 10 months of follow-up. Surgical biopsy confirmed FD. Several case reports describe FDG-avid FD, but conversion of metabolic activity late in life is probably unusual.

Original languageEnglish (US)
Pages (from-to)909-911
Number of pages3
JournalClinical nuclear medicine
Volume33
Issue number12
DOIs
StatePublished - Dec 1 2008

Keywords

  • Conversion
  • FDG PET
  • FDG positive
  • Fibrous dysplasia
  • Lytic bone lesion
  • Skull

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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