Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol

Dharmpal S. Dodd, Alan P. Kozikowski

Research output: Contribution to journalArticle


An efficient method for the direct conversion of alcohols to guanidines is presented. A variety of alcohols react with 1 and 2 under Mitsunobu conditions to give the corresponding guanidines in high yield.

Original languageEnglish (US)
Pages (from-to)977-980
Number of pages4
JournalTetrahedron Letters
Issue number7
StatePublished - Feb 14 1994


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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