Abstract
The author has developed a sustained-release polymer system that is implanted directly at the site of the brain tumor and thus bypasses the blood-brain barrier and achieves very high local concentrations of drug with minimal systemic toxicity. The polymer, BIODEL, is a polyanhydride, poly(bis(p-carboxy-phenoxy propane anhydride) sebacic acid), (PCPP-SA). The polyanhydrides have a number of features that make them particularly suitable for this study.
| Original language | English (US) |
|---|---|
| Number of pages | 1 |
| Journal | American Chemical Society, Polymer Preprints, Division of Polymer Chemistry |
| Volume | 31 |
| Issue number | 1 |
| State | Published - Apr 1 1990 |
| Event | Papers Presented at the Boston, Massachusetts Meeting of ACS 1989 - Boston, MA, USA Duration: Apr 22 1989 → Apr 27 1989 |
ASJC Scopus subject areas
- Polymers and Plastics