Contribution of tryptophan to the biologic properties of anti-dinitrophenyl antibody

Diane Griffin, D. K. Tachibana, B. Nelson, L. T. Rosenberg

Research output: Contribution to journalArticlepeer-review

Abstract

Labeling of a few trytophan residues with 2-OH-5-NO2 benzylbromide decreases the complement fixing and sensitizing capacity of anti-dinitrophenyl antibody, leaving the antibody combining site unaffected. This suggests a role for a trytophan containing peptide in the affected activities.

Original languageEnglish (US)
Pages (from-to)23-30
Number of pages8
JournalImmunochemistry
Volume4
Issue number1
DOIs
StatePublished - Jan 1967
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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