Contribution of tryptophan to the biologic properties of anti-dinitrophenyl antibody

Diane Griffin; D. K. Tachibana; B. Nelson; L. T. Rosenberg

doi:10.1016/0019-2791(67)90193-0

Contribution of tryptophan to the biologic properties of anti-dinitrophenyl antibody

Diane Griffin, D. K. Tachibana, B. Nelson, L. T. Rosenberg

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Labeling of a few trytophan residues with 2-OH-5-NO₂ benzylbromide decreases the complement fixing and sensitizing capacity of anti-dinitrophenyl antibody, leaving the antibody combining site unaffected. This suggests a role for a trytophan containing peptide in the affected activities.

Original language	English (US)
Pages (from-to)	23-30
Number of pages	8
Journal	Immunochemistry
Volume	4
Issue number	1
DOIs	https://doi.org/10.1016/0019-2791(67)90193-0
State	Published - Jan 1967
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/0019-2791(67)90193-0

Cite this

@article{f2b8c74bb48f472eaabcf2751d11595a,

title = "Contribution of tryptophan to the biologic properties of anti-dinitrophenyl antibody",

abstract = "Labeling of a few trytophan residues with 2-OH-5-NO2 benzylbromide decreases the complement fixing and sensitizing capacity of anti-dinitrophenyl antibody, leaving the antibody combining site unaffected. This suggests a role for a trytophan containing peptide in the affected activities.",

author = "Diane Griffin and Tachibana, {D. K.} and B. Nelson and Rosenberg, {L. T.}",

note = "Funding Information: a Supported by grants from the National Institutes of Health (AI-05316 and AI-82). 23",

year = "1967",

month = jan,

doi = "10.1016/0019-2791(67)90193-0",

language = "English (US)",

volume = "4",

pages = "23--30",

journal = "Immunochemistry",

issn = "0019-2791",

publisher = "Elsevier Limited",

number = "1",

}

TY - JOUR

T1 - Contribution of tryptophan to the biologic properties of anti-dinitrophenyl antibody

AU - Griffin, Diane

AU - Tachibana, D. K.

AU - Nelson, B.

AU - Rosenberg, L. T.

N1 - Funding Information: a Supported by grants from the National Institutes of Health (AI-05316 and AI-82). 23

PY - 1967/1

Y1 - 1967/1

N2 - Labeling of a few trytophan residues with 2-OH-5-NO2 benzylbromide decreases the complement fixing and sensitizing capacity of anti-dinitrophenyl antibody, leaving the antibody combining site unaffected. This suggests a role for a trytophan containing peptide in the affected activities.

AB - Labeling of a few trytophan residues with 2-OH-5-NO2 benzylbromide decreases the complement fixing and sensitizing capacity of anti-dinitrophenyl antibody, leaving the antibody combining site unaffected. This suggests a role for a trytophan containing peptide in the affected activities.

UR - http://www.scopus.com/inward/record.url?scp=0014038378&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014038378&partnerID=8YFLogxK

U2 - 10.1016/0019-2791(67)90193-0

DO - 10.1016/0019-2791(67)90193-0

M3 - Article

C2 - 6030411

AN - SCOPUS:0014038378

SN - 0019-2791

VL - 4

SP - 23

EP - 30

JO - Immunochemistry

JF - Immunochemistry

IS - 1

ER -

Contribution of tryptophan to the biologic properties of anti-dinitrophenyl antibody

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this