Contrast sensitivity after wavefront-guided and wavefront-optimized PRK and LASIK for myopia and myopic astigmatism

Denise S. Ryan, Rose K. Sia, Jeff Rabin, Bruce A. Rivers, Richard D. Stutzman, Joseph F. Pasternak, Jennifer B. Eaddy, Lorie A. Logan, Kraig Bower

Research output: Contribution to journalArticle

Abstract

PURPOSE: To compare contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimized photorefractive keratectomy (PRK) or LASIK for the treatment of myopia or myopic astigmatism 12 months after surgery. METHODS: In a prospective, randomized clinical trial, 215 participants with myopia ranging from -0.50 to -7.25 diopters (D) and less than -3.50 D of manifest astigmatism electing to undergo either LASIK or PRK were randomized to receive wavefront-guided or wavefront-optimized treatment. Corrected Super Vision Test (Precision Vision, La Salle, IL) high contrast and small letter contrast sensitivity, uncorrected postoperative contrast sensitivity function, and uncorrected and corrected distance visual acuity were measured preoperatively and at 1, 3, 6, and 12 months postoperatively. RESULTS: There was a significant difference within each of the four groups over time when measuring high contrast visual acuity (P < .001) and small letter contrast sensitivity (P < .001), with the most significant decrease occurring 1 month postoperatively. However, there were no significant differences when comparing the four groups for high contrast sensitivity (P = .22) or small letter contrast sensitivity (P = .06). The area under the logarithm of contrast sensitivity function did not differ significantly over time (P = .09) or between groups (P = .16). A pairwise comparison of preoperative to 12-month CDVA showed a significant improvement in all groups (P < .017). The change in CDVA was also significantly different between groups as determined by one-way analysis of variance (P = .003). CONCLUSIONS: Wavefront-guided and wavefront-optimized PRK and LASIK procedures maintained high contrast, small letter contrast sensitivity, and contrast sensitivity function 12 months postoperatively. Although the recovery period for visual performance was longer for PRK versus LASIK, there was no significant difference in treatment type or treatment profile at 12 months postoperatively.

Original languageEnglish (US)
Pages (from-to)590-596
Number of pages7
JournalJournal of Refractive Surgery
Volume34
Issue number9
DOIs
StatePublished - Sep 1 2018

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Photorefractive Keratectomy
Laser In Situ Keratomileusis
Contrast Sensitivity
Astigmatism
Myopia
Visual Acuity
Vision Tests
Therapeutics
Analysis of Variance
Randomized Controlled Trials

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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Contrast sensitivity after wavefront-guided and wavefront-optimized PRK and LASIK for myopia and myopic astigmatism. / Ryan, Denise S.; Sia, Rose K.; Rabin, Jeff; Rivers, Bruce A.; Stutzman, Richard D.; Pasternak, Joseph F.; Eaddy, Jennifer B.; Logan, Lorie A.; Bower, Kraig.

In: Journal of Refractive Surgery, Vol. 34, No. 9, 01.09.2018, p. 590-596.

Research output: Contribution to journalArticle

Ryan, Denise S. ; Sia, Rose K. ; Rabin, Jeff ; Rivers, Bruce A. ; Stutzman, Richard D. ; Pasternak, Joseph F. ; Eaddy, Jennifer B. ; Logan, Lorie A. ; Bower, Kraig. / Contrast sensitivity after wavefront-guided and wavefront-optimized PRK and LASIK for myopia and myopic astigmatism. In: Journal of Refractive Surgery. 2018 ; Vol. 34, No. 9. pp. 590-596.
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AU - Ryan, Denise S.

AU - Sia, Rose K.

AU - Rabin, Jeff

AU - Rivers, Bruce A.

AU - Stutzman, Richard D.

AU - Pasternak, Joseph F.

AU - Eaddy, Jennifer B.

AU - Logan, Lorie A.

AU - Bower, Kraig

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N2 - PURPOSE: To compare contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimized photorefractive keratectomy (PRK) or LASIK for the treatment of myopia or myopic astigmatism 12 months after surgery. METHODS: In a prospective, randomized clinical trial, 215 participants with myopia ranging from -0.50 to -7.25 diopters (D) and less than -3.50 D of manifest astigmatism electing to undergo either LASIK or PRK were randomized to receive wavefront-guided or wavefront-optimized treatment. Corrected Super Vision Test (Precision Vision, La Salle, IL) high contrast and small letter contrast sensitivity, uncorrected postoperative contrast sensitivity function, and uncorrected and corrected distance visual acuity were measured preoperatively and at 1, 3, 6, and 12 months postoperatively. RESULTS: There was a significant difference within each of the four groups over time when measuring high contrast visual acuity (P < .001) and small letter contrast sensitivity (P < .001), with the most significant decrease occurring 1 month postoperatively. However, there were no significant differences when comparing the four groups for high contrast sensitivity (P = .22) or small letter contrast sensitivity (P = .06). The area under the logarithm of contrast sensitivity function did not differ significantly over time (P = .09) or between groups (P = .16). A pairwise comparison of preoperative to 12-month CDVA showed a significant improvement in all groups (P < .017). The change in CDVA was also significantly different between groups as determined by one-way analysis of variance (P = .003). CONCLUSIONS: Wavefront-guided and wavefront-optimized PRK and LASIK procedures maintained high contrast, small letter contrast sensitivity, and contrast sensitivity function 12 months postoperatively. Although the recovery period for visual performance was longer for PRK versus LASIK, there was no significant difference in treatment type or treatment profile at 12 months postoperatively.

AB - PURPOSE: To compare contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimized photorefractive keratectomy (PRK) or LASIK for the treatment of myopia or myopic astigmatism 12 months after surgery. METHODS: In a prospective, randomized clinical trial, 215 participants with myopia ranging from -0.50 to -7.25 diopters (D) and less than -3.50 D of manifest astigmatism electing to undergo either LASIK or PRK were randomized to receive wavefront-guided or wavefront-optimized treatment. Corrected Super Vision Test (Precision Vision, La Salle, IL) high contrast and small letter contrast sensitivity, uncorrected postoperative contrast sensitivity function, and uncorrected and corrected distance visual acuity were measured preoperatively and at 1, 3, 6, and 12 months postoperatively. RESULTS: There was a significant difference within each of the four groups over time when measuring high contrast visual acuity (P < .001) and small letter contrast sensitivity (P < .001), with the most significant decrease occurring 1 month postoperatively. However, there were no significant differences when comparing the four groups for high contrast sensitivity (P = .22) or small letter contrast sensitivity (P = .06). The area under the logarithm of contrast sensitivity function did not differ significantly over time (P = .09) or between groups (P = .16). A pairwise comparison of preoperative to 12-month CDVA showed a significant improvement in all groups (P < .017). The change in CDVA was also significantly different between groups as determined by one-way analysis of variance (P = .003). CONCLUSIONS: Wavefront-guided and wavefront-optimized PRK and LASIK procedures maintained high contrast, small letter contrast sensitivity, and contrast sensitivity function 12 months postoperatively. Although the recovery period for visual performance was longer for PRK versus LASIK, there was no significant difference in treatment type or treatment profile at 12 months postoperatively.

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