Contrast-enhanced abdominal MR angiography: Optimization of imaging delay time by automating the detection of contrast material arrival in the aorta

Martin R. Prince, Thomas L. Chenevert, Thomas K F Foo, Frank J. Londy, Jennifer S. Ward, Jeffrey H. Maki

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To improve gadolinium-enhanced magnetic resonance (MR) angiogram quality by automatically synchronizing acquisition of central k- space image data with the arterial phase of contrast material bolus infusion. MATERIALS AND METHODS: A spin-echo pulse sequence with orthogonal 90°and 180°pulses was used to monitor signal in a single 4 x 4 x 12-cm voxel that encompassed a segment of aorta. An increase in signal that corresponded to the arrival of gadolinium was used to trigger three-dimensional, spoiled gradient-echo abdominal MR angiography in 50 adult patients. RESULTS: Arterial signal intensity increased 28-fold with automatic compared to 19- fold with manual triggering (P <.05) at an approximate dose of 0.3 mmol/kg. Automatic triggering with a lower dose (approximately 0.2 mmol/kg) resulted in 20-fold arterial enhancement, which is comparable with enhancement after manual triggering at the high dose. In addition, venous enhancement was less (1.5-fold) with automatic than with manual (3.5-fold) triggering at the same dose (P <.05). CONCLUSION: Automatic triggering results in improved arterial-tovenous contrast. It increases arterial enhancement or enables MR angiograms to be obtained with less contrast material. The authors now routinely use this technique for aortorenal imaging with a gadolinium-based contrast material dose of 20 mmol (40 mL) in patients who weigh more than 50 kg and 10 mmol (20 mL) in patients who weigh less than 50 kg.

Original languageEnglish (US)
Pages (from-to)109-114
Number of pages6
JournalRadiology
Volume203
Issue number1
StatePublished - Apr 1997
Externally publishedYes

Keywords

  • Gadolinium
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), vascular studies

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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