Contraception with an intramuscular estrogen-progestogen preparation administered monthly experience with 4512 cycles of use

Edward E. Wallach, Celso Ramon Garcia

Research output: Contribution to journalArticlepeer-review

Abstract

A parenteral estrogen-progestogen preparation administered intramuscularly at monthly intervals has been studied in 385 patients during 4512 cycles. No pregnancies were established during the use of the medication. The discontinuation rate over the course of 25 months was 43.6%. Thirty-three pregnancies are known to have occurred within 1 to 20 months of discontinuation. Cervical cytology, endometrial histology, and liver function, investigated during the program, were not adversely affected. The most frequent associated effect was prolonged or excessive vaginal bleeding. The preparation and mode of contraception were well tolerated and readily accepted.

Original languageEnglish (US)
Pages (from-to)185-207
Number of pages23
JournalContraception
Volume1
Issue number3
DOIs
StatePublished - Mar 1970
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Contraception with an intramuscular estrogen-progestogen preparation administered monthly experience with 4512 cycles of use'. Together they form a unique fingerprint.

Cite this