Abstract
A parenteral estrogen-progestogen preparation administered intramuscularly at monthly intervals has been studied in 385 patients during 4512 cycles. No pregnancies were established during the use of the medication. The discontinuation rate over the course of 25 months was 43.6%. Thirty-three pregnancies are known to have occurred within 1 to 20 months of discontinuation. Cervical cytology, endometrial histology, and liver function, investigated during the program, were not adversely affected. The most frequent associated effect was prolonged or excessive vaginal bleeding. The preparation and mode of contraception were well tolerated and readily accepted.
Original language | English (US) |
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Pages (from-to) | 185-207 |
Number of pages | 23 |
Journal | Contraception |
Volume | 1 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1970 |
Externally published | Yes |
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology