Continuous negative pressure (CNP) around the chest-wall and lower parts of the body was used to treat progressively severe hypoxemia in a spontaneously breathing adult with diffuse alveolar disease. Therapy with CNP produced a substantial increase in arterial oxygen tension that was sustained and permitted a decrease in oxygen requirements to 40% within 24 hours. There were concomitant decreases in intrapulmonary right-to-left shunt and respiratory frequency. During CNP therapy, no adverse effects on heart rate or blood pressure were detected.
|Original language||English (US)|
|Number of pages||2|
|Journal||JAMA: The Journal of the American Medical Association|
|State||Published - Oct 11 1976|
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