TY - JOUR
T1 - Content validity of the female sexual function index (FSFI) in pre- and postmenopausal women with hypoactive sexual desire disorder
AU - Revicki, Dennis A.
AU - Margolis, Mary K.
AU - Bush, Elizabeth N.
AU - Derogatis, Leonard R.
AU - Hanes, Vladimir
N1 - Funding Information:
This research was supported by Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, NJ, USA.
Funding Information:
Dennis Revicki, Mary Kay Margolis, and Elizabeth Bush are employees of United BioSource Corporation, which received funding from Boehringer Ingelheim to conduct the study. Vladimir Hanes is an employee of Boehringer Ingelheim. Leonard R. DeRogatis has received research funding from Boehringer Ingelheim.
PY - 2011/8
Y1 - 2011/8
N2 - Introduction. The Female Sexual Function Index (FSFI) has consistently been shown to have discriminant validity, test-retest reliability, and internal consistency as a measure of female sexual function. However, the content validity (relevance, clarity, comprehensiveness) of the instrument in women with hypoactive sexual desire disorder (HSDD) must also be established. Aim. The aim of this study were to assess the content validity of the FSFI, specifically the FSFI desire domain, in pre- and postmenopausal women with HSDD. Methods. Two single-visit content validation studies were conducted in the United States. Eligible premenopausal (both studies) and postmenopausal (second study only) women with HSDD completed the FSFI followed by one-on-one, face-to-face cognitive debriefing interviews including open-ended questions to capture information on their perceptions of the instrument. Information on women's experiences of decreased sexual desire was also captured. Main Outcome Measures. The main outcome measures of this study were the women's ratings of the clarity, ease of understanding, comprehensiveness, and relevance of the 19 items of the FSFI. Results. Interviews with 15 premenopausal women (first study), and 30 pre- and 31 postmenopausal women (second study), were analyzed. Across the whole sample, most women (80-100%) found every item of the FSFI clear and easy to understand. The majority (53-70%) felt that the FSFI captured all their feelings about decreased sexual desire and other sexual problems, and most (84-90%) indicated that additional questions were unnecessary. Most women in both studies (93-100%) reported that the two items comprising the FSFI desire domain were clear, easy to understand, and were relevant to them. The majority of women thought that a recall period of ≥7 days is most relevant for recall of their sexual desire. Conclusions. These studies establish the content validity of the FSFI in pre- and postmenopausal women with HSDD, supporting the use of this instrument as a measure of sexual function in women with this condition.
AB - Introduction. The Female Sexual Function Index (FSFI) has consistently been shown to have discriminant validity, test-retest reliability, and internal consistency as a measure of female sexual function. However, the content validity (relevance, clarity, comprehensiveness) of the instrument in women with hypoactive sexual desire disorder (HSDD) must also be established. Aim. The aim of this study were to assess the content validity of the FSFI, specifically the FSFI desire domain, in pre- and postmenopausal women with HSDD. Methods. Two single-visit content validation studies were conducted in the United States. Eligible premenopausal (both studies) and postmenopausal (second study only) women with HSDD completed the FSFI followed by one-on-one, face-to-face cognitive debriefing interviews including open-ended questions to capture information on their perceptions of the instrument. Information on women's experiences of decreased sexual desire was also captured. Main Outcome Measures. The main outcome measures of this study were the women's ratings of the clarity, ease of understanding, comprehensiveness, and relevance of the 19 items of the FSFI. Results. Interviews with 15 premenopausal women (first study), and 30 pre- and 31 postmenopausal women (second study), were analyzed. Across the whole sample, most women (80-100%) found every item of the FSFI clear and easy to understand. The majority (53-70%) felt that the FSFI captured all their feelings about decreased sexual desire and other sexual problems, and most (84-90%) indicated that additional questions were unnecessary. Most women in both studies (93-100%) reported that the two items comprising the FSFI desire domain were clear, easy to understand, and were relevant to them. The majority of women thought that a recall period of ≥7 days is most relevant for recall of their sexual desire. Conclusions. These studies establish the content validity of the FSFI in pre- and postmenopausal women with HSDD, supporting the use of this instrument as a measure of sexual function in women with this condition.
KW - FSFI
KW - Female Sexual Function Index
KW - HSDD
KW - Hypoactive Sexual Desire Disorder
KW - PRO
KW - Patient-Reported Outcome
KW - Validation
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U2 - 10.1111/j.1743-6109.2011.02312.x
DO - 10.1111/j.1743-6109.2011.02312.x
M3 - Article
C2 - 21595836
AN - SCOPUS:79960840742
SN - 1743-6095
VL - 8
SP - 2237
EP - 2245
JO - Journal of Sexual Medicine
JF - Journal of Sexual Medicine
IS - 8
ER -