Construction of a digital and physical mouse model aimed at the study of electrical shock

Thu T A Nguyen, Jeffrey W. Shupp, Lauren T. Moffatt, Jessica C. Ramella-Roman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical methods have been used to investigate electrical injury on animal models such as live mice, rats, and rabbits. Here we introduce a completely digital phantom of a mouse, with the aim of investigating electrical injury through spectroscopic imaging techniques. The basis of our phantom is a three-dimensional digital mouse reconstructed from co-registered computed tomographic images and cryosection by a different group. Image processing algorithms were applied to make the model suitable to Finite Element Analysis of thermal and electrical transport. Our digital model is capable of simulating temperature, voltage, current changes along the animal body during and after electrical shocks.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume8945
ISBN (Print)9780819498588
DOIs
StatePublished - 2014
Externally publishedYes
EventDesign and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI - San Francisco, CA, United States
Duration: Feb 1 2014Feb 2 2014

Other

OtherDesign and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI
CountryUnited States
CitySan Francisco, CA
Period2/1/142/2/14

Keywords

  • Digimouse
  • Electrical Shock
  • Thermal imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Nguyen, T. T. A., Shupp, J. W., Moffatt, L. T., & Ramella-Roman, J. C. (2014). Construction of a digital and physical mouse model aimed at the study of electrical shock. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8945). [894508] SPIE. https://doi.org/10.1117/12.2039661