TY - JOUR
T1 - Consolidation of motor memory
AU - Krakauer, John W.
AU - Shadmehr, Reza
N1 - Funding Information:
This work was supported by National Institute of Neurological Disorders and Stroke Grants K23-NS02138 (to J.W.K.), and R01-NS037422 (to R.S.). We thank Javier Medina and Michael Mauk for insightful discussions, and Toni Pearson for critical comments on the manuscript.
PY - 2006/1
Y1 - 2006/1
N2 - An issue of great recent interest is whether motor memory consolidates in a manner analogous to declarative memory - that is, with the formation of a memory that progresses over time from a fragile state, which is susceptible to interference by a lesion or a conflicting motor task, to a stabilized state, which is resistant to such interference. Here, we first review studies that examine the anatomical basis for motor consolidation. Evidence implicates cerebellar circuitry in two types of associative motor learning - eyelid conditioning and vestibulo-ocular reflex adaptation - and implicates primary motor cortex in skilled finger movements. We also review evidence for and against a consolidation process for adaptation of arm movements. We propose that contradictions have arisen because consolidation can be masked by inhibition of memory retrieval.
AB - An issue of great recent interest is whether motor memory consolidates in a manner analogous to declarative memory - that is, with the formation of a memory that progresses over time from a fragile state, which is susceptible to interference by a lesion or a conflicting motor task, to a stabilized state, which is resistant to such interference. Here, we first review studies that examine the anatomical basis for motor consolidation. Evidence implicates cerebellar circuitry in two types of associative motor learning - eyelid conditioning and vestibulo-ocular reflex adaptation - and implicates primary motor cortex in skilled finger movements. We also review evidence for and against a consolidation process for adaptation of arm movements. We propose that contradictions have arisen because consolidation can be masked by inhibition of memory retrieval.
UR - http://www.scopus.com/inward/record.url?scp=30344462354&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=30344462354&partnerID=8YFLogxK
U2 - 10.1016/j.tins.2005.10.003
DO - 10.1016/j.tins.2005.10.003
M3 - Review article
C2 - 16290273
AN - SCOPUS:30344462354
VL - 29
SP - 58
EP - 64
JO - Trends in Neurosciences
JF - Trends in Neurosciences
SN - 0378-5912
IS - 1
ER -