Considerations for sequencing analyses of pancreatic cancer progression and metastasis

Alvin Makohon-Moore, Christine A. Iacobuzio-Donahue

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Sequencing analyses have been invaluable in identifying the genes associated with pancreatic carcinogenesis. However, whereas gene discovery related to carcinogenesis can be fairly straightforward, there are several additional aspects of experimental design that need to be considered when performing genetic analyses of metastatic disease. This chapter aims to review these issues and provide examples of the types of data generated.

Original languageEnglish (US)
Title of host publicationPancreatic Cancer
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages121-129
Number of pages9
ISBN (Print)9781627032865
DOIs
StatePublished - 2013

Publication series

NameMethods in Molecular Biology
Volume980
ISSN (Print)1064-3745

Keywords

  • Comparative lesion sequencing
  • Genetics
  • Metastasis
  • Pancreatic cancer

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    Makohon-Moore, A., & Iacobuzio-Donahue, C. A. (2013). Considerations for sequencing analyses of pancreatic cancer progression and metastasis. In Pancreatic Cancer: Methods and Protocols (pp. 121-129). (Methods in Molecular Biology; Vol. 980). Humana Press Inc.. https://doi.org/10.1007/978-1-62703-287-2_6