Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist

Rodolfo Montironi, Elizabeth H. Hammond, Daniel W. Lin, John L. Gore, John R. Srigley, Hema Samaratunga, Lars Egevad, Mark A. Rubin, John Nacey, Laurence Klotz, Howard Sandler, Anthony L. Zietman, Stuart Holden, Peter A. Humphrey, Andrew J. Evans, Brett Delahunt, Jesse K. McKenney, Daniel Berney, Thomas M. Wheeler, Arul ChinnaiyanLawrence True, Beatrice Knudsen, Jonathan I. Epstein, Mahul B. Amin

Research output: Contribution to journalReview articlepeer-review

Abstract

Active surveillance (AS) is an important management option for men with low-risk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts matures. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and consistently reported by surgical pathologists. This report highlights the importance of accurate pathology reporting as a critical component of these protocols.

Original languageEnglish (US)
Pages (from-to)623-628
Number of pages6
JournalVirchows Archiv
Volume465
Issue number6
DOIs
StatePublished - Nov 27 2014

Keywords

  • Accurate pathology reporting
  • Active surveillance
  • Localized prostate cancer
  • Low-risk prostate cancer
  • Overtreatment

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Cell Biology

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