Conjunctival vessel abnormalities in sickle cell diseases: the influence of age and genotype

W. C.A. Siqueira; M. S. Figueiredo; A. A.V. Cruz; F. F. Costa; M. A. Zago

doi:10.1111/j.1755-3768.1990.tb04779.x

Conjunctival vessel abnormalities in sickle cell diseases: the influence of age and genotype

W. C.A. Siqueira, M. S. Figueiredo, A. A.V. Cruz, F. F. Costa, M. A. Zago

Research output: Contribution to journal › Article › peer-review

Abstract

Abstract Conjunctival vessels were examined with a slit‐lamp and the abnormalities were graded in 77 patients with sickle cell diseases, including 48 with sickle cell anaemia, 17 with sickle cell β°‐thalassaemia and 12 with HbS/HbC disease. The study demonstrated the occurrence of similar conjunctival vessel abnormalities for the three sickle cell diseases which are, however, more severe in HbS homozygotes than in the two other genotypes. An increase of the severity of the vascular abnormalities with the increase of patient age was also observed for HbS homozygotes. The data suggest that the conjunctival lesions accumulate and increase in severity in a similar fashion as other tissue damages observed in sickle cell diseases. 1990 Institution Acta Ophthalmologica Scandinavica

Original language	English (US)
Pages (from-to)	515-518
Number of pages	4
Journal	Acta Ophthalmologica
Volume	68
Issue number	5
DOIs	https://doi.org/10.1111/j.1755-3768.1990.tb04779.x
State	Published - Oct 1990
Externally published	Yes

Keywords

conjunctiva
haemoglobin S
microvasculature
sickle cell anemia

ASJC Scopus subject areas

Ophthalmology

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10.1111/j.1755-3768.1990.tb04779.x

Cite this

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title = "Conjunctival vessel abnormalities in sickle cell diseases: the influence of age and genotype",

abstract = "Abstract Conjunctival vessels were examined with a slit‐lamp and the abnormalities were graded in 77 patients with sickle cell diseases, including 48 with sickle cell anaemia, 17 with sickle cell β°‐thalassaemia and 12 with HbS/HbC disease. The study demonstrated the occurrence of similar conjunctival vessel abnormalities for the three sickle cell diseases which are, however, more severe in HbS homozygotes than in the two other genotypes. An increase of the severity of the vascular abnormalities with the increase of patient age was also observed for HbS homozygotes. The data suggest that the conjunctival lesions accumulate and increase in severity in a similar fashion as other tissue damages observed in sickle cell diseases. 1990 Institution Acta Ophthalmologica Scandinavica",

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AU - Siqueira, W. C.A.

AU - Figueiredo, M. S.

AU - Cruz, A. A.V.

AU - Costa, F. F.

AU - Zago, M. A.

PY - 1990/10

Y1 - 1990/10

N2 - Abstract Conjunctival vessels were examined with a slit‐lamp and the abnormalities were graded in 77 patients with sickle cell diseases, including 48 with sickle cell anaemia, 17 with sickle cell β°‐thalassaemia and 12 with HbS/HbC disease. The study demonstrated the occurrence of similar conjunctival vessel abnormalities for the three sickle cell diseases which are, however, more severe in HbS homozygotes than in the two other genotypes. An increase of the severity of the vascular abnormalities with the increase of patient age was also observed for HbS homozygotes. The data suggest that the conjunctival lesions accumulate and increase in severity in a similar fashion as other tissue damages observed in sickle cell diseases. 1990 Institution Acta Ophthalmologica Scandinavica

AB - Abstract Conjunctival vessels were examined with a slit‐lamp and the abnormalities were graded in 77 patients with sickle cell diseases, including 48 with sickle cell anaemia, 17 with sickle cell β°‐thalassaemia and 12 with HbS/HbC disease. The study demonstrated the occurrence of similar conjunctival vessel abnormalities for the three sickle cell diseases which are, however, more severe in HbS homozygotes than in the two other genotypes. An increase of the severity of the vascular abnormalities with the increase of patient age was also observed for HbS homozygotes. The data suggest that the conjunctival lesions accumulate and increase in severity in a similar fashion as other tissue damages observed in sickle cell diseases. 1990 Institution Acta Ophthalmologica Scandinavica

KW - conjunctiva

KW - haemoglobin S

KW - microvasculature

KW - sickle cell anemia

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Conjunctival vessel abnormalities in sickle cell diseases: the influence of age and genotype

Abstract

Keywords

ASJC Scopus subject areas

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