Conjunctival Nodules Associated with Onchocerciasis

Richard D. Semba, Susan H. Day, William H. Spencer

Research output: Contribution to journalArticle


A 14-year-old native of Ethiopia with previously treated onchocerciasis moved to California where he was examined for evidence of persisting nematode infestation. Skin and conjunctival biopsy specimens initially disclosed no abnormalities. Subsequently, conjunctival nodules developed, and a biopsy specimen of one of these revealed microfilariae of Onchocerca volvulus lying adjacent to a necrotic eosinophilic granulomatous inflammatory nodule. To our knowledge, nodules of this type have not heretofore been reported to be a notable feature of ocular onchocerciasis. This type of inflammation has a relationship to degenerating microfilaria in onchocerciasis and in other nematode infestation.

Original languageEnglish (US)
Pages (from-to)823-824
Number of pages2
JournalArchives of ophthalmology
Issue number6
StatePublished - Jun 1985

ASJC Scopus subject areas

  • Ophthalmology

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