Congenital malformations associated with the administration of oral anticoagulants during pregnancy

Paul S. Lietman, J. M. Pettifor, R. Benson

Research output: Contribution to journalArticle

Abstract

Three small infants whose mothers had received oral anticoagulant therapy during the first trimester of pregnancy are described. These infants all had hypoplasia of the nasal bones, and two had stippling of epiphyses and bones and deformities of the bones of the hand. One child is mentally retarded. It is suggested that these abnormalities may be related to maternal oral anticoagulant therapy during the first trimester.

Original languageEnglish (US)
Pages (from-to)459-462
Number of pages4
JournalJournal of Pediatrics
Volume86
Issue number3
DOIs
StatePublished - 1975
Externally publishedYes

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First Pregnancy Trimester
Anticoagulants
Oral Administration
Mothers
Nasal Bone
Hand Bones
Pregnancy
Epiphyses
Mentally Disabled Persons
Bone and Bones
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Congenital malformations associated with the administration of oral anticoagulants during pregnancy. / Lietman, Paul S.; Pettifor, J. M.; Benson, R.

In: Journal of Pediatrics, Vol. 86, No. 3, 1975, p. 459-462.

Research output: Contribution to journalArticle

Lietman, Paul S. ; Pettifor, J. M. ; Benson, R. / Congenital malformations associated with the administration of oral anticoagulants during pregnancy. In: Journal of Pediatrics. 1975 ; Vol. 86, No. 3. pp. 459-462.
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