Congenital Grouped Pigmentation of the Retina: Histopathologic Description and Report of a Case

Jerry A. Shields, Mark O M Tso

Research output: Contribution to journalArticle

Abstract

Gross examination of an eye removed at autopsy from a 4-year-old child with congenital heart disease revealed typical grouped pigmentation of the retina. Routine light microscopy and flat preparation of the retinal pigment epithelium demonstrated the lesions to consist of focal areas of increased concentration of pigment granules in otherwise normal retinal pigment epithelial cells. The pigment granules were large and football shaped. The overlying photoreceptors showed no abnormalities, possibly explaining the clinical features of normal visual acuity and visual fields in this patient. We believe that this is the first histologic description of congenital grouped pigmentation reported in the English literature. A differential diagnosis and brief review of the pertinent literature are also presented.

Original languageEnglish (US)
Pages (from-to)1153-1155
Number of pages3
JournalArchives of Ophthalmology
Volume93
Issue number11
DOIs
StatePublished - 1975
Externally publishedYes

Fingerprint

Pigmentation
Retina
Literature
Retinal Pigments
Football
Retinal Pigment Epithelium
Visual Fields
Visual Acuity
Microscopy
Autopsy
Heart Diseases
Differential Diagnosis
Epithelial Cells
Light

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Congenital Grouped Pigmentation of the Retina : Histopathologic Description and Report of a Case. / Shields, Jerry A.; Tso, Mark O M.

In: Archives of Ophthalmology, Vol. 93, No. 11, 1975, p. 1153-1155.

Research output: Contribution to journalArticle

@article{a7bb5c533a164a0183787b8cb32c237b,
title = "Congenital Grouped Pigmentation of the Retina: Histopathologic Description and Report of a Case",
abstract = "Gross examination of an eye removed at autopsy from a 4-year-old child with congenital heart disease revealed typical grouped pigmentation of the retina. Routine light microscopy and flat preparation of the retinal pigment epithelium demonstrated the lesions to consist of focal areas of increased concentration of pigment granules in otherwise normal retinal pigment epithelial cells. The pigment granules were large and football shaped. The overlying photoreceptors showed no abnormalities, possibly explaining the clinical features of normal visual acuity and visual fields in this patient. We believe that this is the first histologic description of congenital grouped pigmentation reported in the English literature. A differential diagnosis and brief review of the pertinent literature are also presented.",
author = "Shields, {Jerry A.} and Tso, {Mark O M}",
year = "1975",
doi = "10.1001/archopht.1975.01010020861007",
language = "English (US)",
volume = "93",
pages = "1153--1155",
journal = "JAMA Ophthalmology",
issn = "2168-6165",
publisher = "American Medical Association",
number = "11",

}

TY - JOUR

T1 - Congenital Grouped Pigmentation of the Retina

T2 - Histopathologic Description and Report of a Case

AU - Shields, Jerry A.

AU - Tso, Mark O M

PY - 1975

Y1 - 1975

N2 - Gross examination of an eye removed at autopsy from a 4-year-old child with congenital heart disease revealed typical grouped pigmentation of the retina. Routine light microscopy and flat preparation of the retinal pigment epithelium demonstrated the lesions to consist of focal areas of increased concentration of pigment granules in otherwise normal retinal pigment epithelial cells. The pigment granules were large and football shaped. The overlying photoreceptors showed no abnormalities, possibly explaining the clinical features of normal visual acuity and visual fields in this patient. We believe that this is the first histologic description of congenital grouped pigmentation reported in the English literature. A differential diagnosis and brief review of the pertinent literature are also presented.

AB - Gross examination of an eye removed at autopsy from a 4-year-old child with congenital heart disease revealed typical grouped pigmentation of the retina. Routine light microscopy and flat preparation of the retinal pigment epithelium demonstrated the lesions to consist of focal areas of increased concentration of pigment granules in otherwise normal retinal pigment epithelial cells. The pigment granules were large and football shaped. The overlying photoreceptors showed no abnormalities, possibly explaining the clinical features of normal visual acuity and visual fields in this patient. We believe that this is the first histologic description of congenital grouped pigmentation reported in the English literature. A differential diagnosis and brief review of the pertinent literature are also presented.

UR - http://www.scopus.com/inward/record.url?scp=0016679119&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016679119&partnerID=8YFLogxK

U2 - 10.1001/archopht.1975.01010020861007

DO - 10.1001/archopht.1975.01010020861007

M3 - Article

C2 - 1191104

AN - SCOPUS:0016679119

VL - 93

SP - 1153

EP - 1155

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

SN - 2168-6165

IS - 11

ER -