TY - JOUR
T1 - Congenital Diaphragmatic Hernia and Neonatal Lung Lesions
AU - Kays, David W.
PY - 2006/4
Y1 - 2006/4
N2 - CDH and neonatal lung lesions are increasingly diagnosed during fetal life, and expanded use of three-dimensional ultrasound and fetal MRI have improved diagnostic detail and accuracy. Chromosomal abnormalities and severe congenital heart lesions negatively impact CDH outcome, but survival at several centers that have abandoned hyperventilation in favor of strict lung protective strategies exceeds 80% in patients who have isolated CDH. Congenital lung lesions range from small, asymptomatic imaging abnormalities to large, space-occupying lesions that cause fetal hydrops. Symptomatic lesions should be resected during infancy, and resection remains the standard for most asymptomatic lesions. Increasing numbers of reports indicate that small, asymptomatic lesions are being treated with observation and follow-up alone, and maturation of this literature is expected in the years to come.
AB - CDH and neonatal lung lesions are increasingly diagnosed during fetal life, and expanded use of three-dimensional ultrasound and fetal MRI have improved diagnostic detail and accuracy. Chromosomal abnormalities and severe congenital heart lesions negatively impact CDH outcome, but survival at several centers that have abandoned hyperventilation in favor of strict lung protective strategies exceeds 80% in patients who have isolated CDH. Congenital lung lesions range from small, asymptomatic imaging abnormalities to large, space-occupying lesions that cause fetal hydrops. Symptomatic lesions should be resected during infancy, and resection remains the standard for most asymptomatic lesions. Increasing numbers of reports indicate that small, asymptomatic lesions are being treated with observation and follow-up alone, and maturation of this literature is expected in the years to come.
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U2 - 10.1016/j.suc.2005.12.016
DO - 10.1016/j.suc.2005.12.016
M3 - Review article
C2 - 16580927
AN - SCOPUS:33645845730
VL - 86
SP - 329
EP - 352
JO - Surgical Clinics of North America
JF - Surgical Clinics of North America
SN - 0039-6109
IS - 2
ER -