Congenital alveolar capillary dysplasia - An unusual cause of respiratory distress in the newborn

C. G. Janney, F. B. Askin, C. Kuhn

Research output: Contribution to journalArticle

Abstract

The clinical and anatomical features of a patient with an unusual pulmonary malformation, is reported. The clinical course was consistent with the syndrome of persistent fetal circulation; morphologically, however, the patient was found to have a unique form of pulmonary dysplasia. Failure of formation and ingrowth of alveolar capillaries led to absence of normal air-blood barriers in this term infant. In addition anomalous veins were present in the bronchovascular bundles. Morphometric study indicated that the lungs were otherwise mature. This selective deficiency and dysplasia suggests that distal pulmonary epithelial and vascular development operate under separate control mechanisms.

Original languageEnglish (US)
Pages (from-to)722-727
Number of pages6
JournalAmerican journal of clinical pathology
Volume76
Issue number5
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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