Conformal radiofrequency ablation to validate ultrasound thermometry

Chloé Audigier, Younsu Kim, Jens Ziegle, Michael Friebe, Emad Boctor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Thermal ablation is a clinical procedure that aims at destroying pathological tissue minimally invasively through temperature changes. Temperature monitoring during the treatment is instrumental to achieve a precise and successful ablation procedure: ensuring a complete target ablation while preserving as much healthy tissue as possible. Ultrasound (US) is a promising low cost and portable modality, that could provide real-time temperature monitoring. However, the validation of such a technique is challenging. It is usually done with thermometers. They provide temperature measurements with good temporal resolution but only at a few local points. Magnetic Resonance Imaging (MRI) is the gold standard in term of temperature monitoring nowadays. It could also be used for validation of other thermometry techniques with a more accurate spatial resolution, but it requires MR-compatible devices. In this paper, we propose to leverage the use of a novel bipolar radiofrequency (RF) ablation device that provides 10 different ablation shapes to validate an ultrasound-based temperature monitoring method. The monitoring method relies on an external ultrasound element integrated with the bipolar RF ablation probe. This element send through the ablated tissues ultrasound waves that carry time-of-flight information. The ultrasound waves are collected by a clinical diagnostic ultrasound probe and can be related to the changes in temperature due to the ablation since ultrasound propagation velocity in biological tissue changes as temperature increases. We use this ultrasound-based method to monitor temperature during RF ablation. First on simulation data and then on two ex-vivo porcine liver experiments. Those dataset are used to show that we can validate the proposed temperature reconstruction method using the novel conformal radiofrequency ablation device by generating different ablation shapes.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2019
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
EditorsBaowei Fei, Cristian A. Linte
PublisherSPIE
ISBN (Electronic)9781510625495
DOIs
StatePublished - Jan 1 2019
EventMedical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, United States
Duration: Feb 17 2019Feb 19 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10951
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CitySan Diego
Period2/17/192/19/19

Fingerprint

Thermometry
Ablation
ablation
temperature measurement
Ultrasonics
Temperature
Monitoring
Tissue
temperature
Equipment and Supplies
Thermometers
probes
propagation velocity
data simulation
thermometers
temporal resolution
liver
Temperature measurement
Liver
preserving

Keywords

  • Computational modeling
  • Radiofrequency Ablation (RFA)
  • Thermal Ablation
  • Ultrasound thermal monitoring
  • Validation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Audigier, C., Kim, Y., Ziegle, J., Friebe, M., & Boctor, E. (2019). Conformal radiofrequency ablation to validate ultrasound thermometry. In B. Fei, & C. A. Linte (Eds.), Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling [1095122] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10951). SPIE. https://doi.org/10.1117/12.2512788

Conformal radiofrequency ablation to validate ultrasound thermometry. / Audigier, Chloé; Kim, Younsu; Ziegle, Jens; Friebe, Michael; Boctor, Emad.

Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. ed. / Baowei Fei; Cristian A. Linte. SPIE, 2019. 1095122 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Audigier, C, Kim, Y, Ziegle, J, Friebe, M & Boctor, E 2019, Conformal radiofrequency ablation to validate ultrasound thermometry. in B Fei & CA Linte (eds), Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling., 1095122, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10951, SPIE, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling, San Diego, United States, 2/17/19. https://doi.org/10.1117/12.2512788
Audigier C, Kim Y, Ziegle J, Friebe M, Boctor E. Conformal radiofrequency ablation to validate ultrasound thermometry. In Fei B, Linte CA, editors, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. SPIE. 2019. 1095122. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2512788
Audigier, Chloé ; Kim, Younsu ; Ziegle, Jens ; Friebe, Michael ; Boctor, Emad. / Conformal radiofrequency ablation to validate ultrasound thermometry. Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. editor / Baowei Fei ; Cristian A. Linte. SPIE, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
@inproceedings{7596e79b83a440a5a38861e5f4c64484,
title = "Conformal radiofrequency ablation to validate ultrasound thermometry",
abstract = "Thermal ablation is a clinical procedure that aims at destroying pathological tissue minimally invasively through temperature changes. Temperature monitoring during the treatment is instrumental to achieve a precise and successful ablation procedure: ensuring a complete target ablation while preserving as much healthy tissue as possible. Ultrasound (US) is a promising low cost and portable modality, that could provide real-time temperature monitoring. However, the validation of such a technique is challenging. It is usually done with thermometers. They provide temperature measurements with good temporal resolution but only at a few local points. Magnetic Resonance Imaging (MRI) is the gold standard in term of temperature monitoring nowadays. It could also be used for validation of other thermometry techniques with a more accurate spatial resolution, but it requires MR-compatible devices. In this paper, we propose to leverage the use of a novel bipolar radiofrequency (RF) ablation device that provides 10 different ablation shapes to validate an ultrasound-based temperature monitoring method. The monitoring method relies on an external ultrasound element integrated with the bipolar RF ablation probe. This element send through the ablated tissues ultrasound waves that carry time-of-flight information. The ultrasound waves are collected by a clinical diagnostic ultrasound probe and can be related to the changes in temperature due to the ablation since ultrasound propagation velocity in biological tissue changes as temperature increases. We use this ultrasound-based method to monitor temperature during RF ablation. First on simulation data and then on two ex-vivo porcine liver experiments. Those dataset are used to show that we can validate the proposed temperature reconstruction method using the novel conformal radiofrequency ablation device by generating different ablation shapes.",
keywords = "Computational modeling, Radiofrequency Ablation (RFA), Thermal Ablation, Ultrasound thermal monitoring, Validation",
author = "Chlo{\'e} Audigier and Younsu Kim and Jens Ziegle and Michael Friebe and Emad Boctor",
year = "2019",
month = "1",
day = "1",
doi = "10.1117/12.2512788",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Baowei Fei and Linte, {Cristian A.}",
booktitle = "Medical Imaging 2019",

}

TY - GEN

T1 - Conformal radiofrequency ablation to validate ultrasound thermometry

AU - Audigier, Chloé

AU - Kim, Younsu

AU - Ziegle, Jens

AU - Friebe, Michael

AU - Boctor, Emad

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Thermal ablation is a clinical procedure that aims at destroying pathological tissue minimally invasively through temperature changes. Temperature monitoring during the treatment is instrumental to achieve a precise and successful ablation procedure: ensuring a complete target ablation while preserving as much healthy tissue as possible. Ultrasound (US) is a promising low cost and portable modality, that could provide real-time temperature monitoring. However, the validation of such a technique is challenging. It is usually done with thermometers. They provide temperature measurements with good temporal resolution but only at a few local points. Magnetic Resonance Imaging (MRI) is the gold standard in term of temperature monitoring nowadays. It could also be used for validation of other thermometry techniques with a more accurate spatial resolution, but it requires MR-compatible devices. In this paper, we propose to leverage the use of a novel bipolar radiofrequency (RF) ablation device that provides 10 different ablation shapes to validate an ultrasound-based temperature monitoring method. The monitoring method relies on an external ultrasound element integrated with the bipolar RF ablation probe. This element send through the ablated tissues ultrasound waves that carry time-of-flight information. The ultrasound waves are collected by a clinical diagnostic ultrasound probe and can be related to the changes in temperature due to the ablation since ultrasound propagation velocity in biological tissue changes as temperature increases. We use this ultrasound-based method to monitor temperature during RF ablation. First on simulation data and then on two ex-vivo porcine liver experiments. Those dataset are used to show that we can validate the proposed temperature reconstruction method using the novel conformal radiofrequency ablation device by generating different ablation shapes.

AB - Thermal ablation is a clinical procedure that aims at destroying pathological tissue minimally invasively through temperature changes. Temperature monitoring during the treatment is instrumental to achieve a precise and successful ablation procedure: ensuring a complete target ablation while preserving as much healthy tissue as possible. Ultrasound (US) is a promising low cost and portable modality, that could provide real-time temperature monitoring. However, the validation of such a technique is challenging. It is usually done with thermometers. They provide temperature measurements with good temporal resolution but only at a few local points. Magnetic Resonance Imaging (MRI) is the gold standard in term of temperature monitoring nowadays. It could also be used for validation of other thermometry techniques with a more accurate spatial resolution, but it requires MR-compatible devices. In this paper, we propose to leverage the use of a novel bipolar radiofrequency (RF) ablation device that provides 10 different ablation shapes to validate an ultrasound-based temperature monitoring method. The monitoring method relies on an external ultrasound element integrated with the bipolar RF ablation probe. This element send through the ablated tissues ultrasound waves that carry time-of-flight information. The ultrasound waves are collected by a clinical diagnostic ultrasound probe and can be related to the changes in temperature due to the ablation since ultrasound propagation velocity in biological tissue changes as temperature increases. We use this ultrasound-based method to monitor temperature during RF ablation. First on simulation data and then on two ex-vivo porcine liver experiments. Those dataset are used to show that we can validate the proposed temperature reconstruction method using the novel conformal radiofrequency ablation device by generating different ablation shapes.

KW - Computational modeling

KW - Radiofrequency Ablation (RFA)

KW - Thermal Ablation

KW - Ultrasound thermal monitoring

KW - Validation

UR - http://www.scopus.com/inward/record.url?scp=85068900966&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068900966&partnerID=8YFLogxK

U2 - 10.1117/12.2512788

DO - 10.1117/12.2512788

M3 - Conference contribution

AN - SCOPUS:85068900966

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2019

A2 - Fei, Baowei

A2 - Linte, Cristian A.

PB - SPIE

ER -