Confocal Laser Endomicroscopy

Ralf Kiesslich; Marcia Irene Canto

doi:10.1016/j.giec.2009.02.007

Confocal Laser Endomicroscopy

Ralf Kiesslich, Marcia Irene Canto

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Endomicroscopy is a newly developed imaging modality, which provides in vivo histology during ongoing endoscopy. This review characterizes the currently available endomicroscopic systems and reflects the clinical value of endomicroscopy for different diseases. Endomicroscopy can be used to discover histology of the mucosal layer at cellular and subcellular resolution. Furthermore, endomicroscopy can be used to observe physiologic and pathophysiologic changes, which offer a newly available insight into the pathogenesis of different diseases. The diagnostic possibilities of endomicroscopy are extensive and highly valuable for every day practice. However, the era of endomicroscopy has just started and it can be anticipated that its role will significantly increase in the future.

Original language	English (US)
Pages (from-to)	261-272
Number of pages	12
Journal	Gastrointestinal Endoscopy Clinics of North America
Volume	19
Issue number	2
DOIs	https://doi.org/10.1016/j.giec.2009.02.007
State	Published - Apr 1 2009

Keywords

Barrett's esophagus
Celiac disease
Colorectal cancer
Confocal laser endoscopy
Endomicroscopy
Fluorescence
Gastric cancer
Gastritis
Miniprobe
Ulcerative colitis

ASJC Scopus subject areas

Gastroenterology

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title = "Confocal Laser Endomicroscopy",

abstract = "Endomicroscopy is a newly developed imaging modality, which provides in vivo histology during ongoing endoscopy. This review characterizes the currently available endomicroscopic systems and reflects the clinical value of endomicroscopy for different diseases. Endomicroscopy can be used to discover histology of the mucosal layer at cellular and subcellular resolution. Furthermore, endomicroscopy can be used to observe physiologic and pathophysiologic changes, which offer a newly available insight into the pathogenesis of different diseases. The diagnostic possibilities of endomicroscopy are extensive and highly valuable for every day practice. However, the era of endomicroscopy has just started and it can be anticipated that its role will significantly increase in the future.",

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