Confocal Laser Endomicroscopy

Ralf Kiesslich, Marcia Irene Canto

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Endomicroscopy is a newly developed imaging modality, which provides in vivo histology during ongoing endoscopy. This review characterizes the currently available endomicroscopic systems and reflects the clinical value of endomicroscopy for different diseases. Endomicroscopy can be used to discover histology of the mucosal layer at cellular and subcellular resolution. Furthermore, endomicroscopy can be used to observe physiologic and pathophysiologic changes, which offer a newly available insight into the pathogenesis of different diseases. The diagnostic possibilities of endomicroscopy are extensive and highly valuable for every day practice. However, the era of endomicroscopy has just started and it can be anticipated that its role will significantly increase in the future.

Original languageEnglish (US)
Pages (from-to)261-272
Number of pages12
JournalGastrointestinal Endoscopy Clinics of North America
Issue number2
StatePublished - Apr 1 2009


  • Barrett's esophagus
  • Celiac disease
  • Colorectal cancer
  • Confocal laser endoscopy
  • Endomicroscopy
  • Fluorescence
  • Gastric cancer
  • Gastritis
  • Miniprobe
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology


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