CONFIGURATIONAL BIASING OF TERTIARY AMIDE IONOPHORES BY ALKALI METAL CHELATION**1**,**2.

Leslie H. Craine, Jeremy Greenblatt, Sarah Woodson, Edwin Hortelano, Morton Raban

Research output: Contribution to journalArticle

Abstract

Configurational analysis can be used as a probe for association constants for chelation of amides with alkali metals. Carbon-13 NMR spectroscopy indicates that tertiary amides, each bearing a triethylene oxide substituent at nitrogen, exist as a mixture of E and Z isomers. Addition of alkali metal cation (KSCN) increases the concentration of species with the Z configuration since this configuration can chelate potassium ion. High-field **1H NMR spectra have been used to determine the chelation constants for amides in the presence of KSCN. It has been determined that (a) the carbonyl oxygen is involved in chelation and (b) the number of ether oxygens on the substituent at nitrogen is the significant factor in the chelating ability of these ionophores.

Original languageEnglish (US)
Pages (from-to)7252-7255
Number of pages4
JournalJournal of the American Chemical Society
Volume105
Issue number25
StatePublished - Jan 1 1983
Externally publishedYes

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Ionophores
Alkali Metals
Alkali metals
Chelation
Amides
Nitrogen
Oxygen
Bearings (structural)
Ether
Cations
Potassium
Magnetic Resonance Spectroscopy
Carbon
Isomers
Ions
Nuclear magnetic resonance spectroscopy
Ethers
Positive ions
Nuclear magnetic resonance
Association reactions

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Craine, L. H., Greenblatt, J., Woodson, S., Hortelano, E., & Raban, M. (1983). CONFIGURATIONAL BIASING OF TERTIARY AMIDE IONOPHORES BY ALKALI METAL CHELATION**1**,**2. Journal of the American Chemical Society, 105(25), 7252-7255.

CONFIGURATIONAL BIASING OF TERTIARY AMIDE IONOPHORES BY ALKALI METAL CHELATION**1**,**2. / Craine, Leslie H.; Greenblatt, Jeremy; Woodson, Sarah; Hortelano, Edwin; Raban, Morton.

In: Journal of the American Chemical Society, Vol. 105, No. 25, 01.01.1983, p. 7252-7255.

Research output: Contribution to journalArticle

Craine, LH, Greenblatt, J, Woodson, S, Hortelano, E & Raban, M 1983, 'CONFIGURATIONAL BIASING OF TERTIARY AMIDE IONOPHORES BY ALKALI METAL CHELATION**1**,**2.', Journal of the American Chemical Society, vol. 105, no. 25, pp. 7252-7255.
Craine LH, Greenblatt J, Woodson S, Hortelano E, Raban M. CONFIGURATIONAL BIASING OF TERTIARY AMIDE IONOPHORES BY ALKALI METAL CHELATION**1**,**2. Journal of the American Chemical Society. 1983 Jan 1;105(25):7252-7255.
Craine, Leslie H. ; Greenblatt, Jeremy ; Woodson, Sarah ; Hortelano, Edwin ; Raban, Morton. / CONFIGURATIONAL BIASING OF TERTIARY AMIDE IONOPHORES BY ALKALI METAL CHELATION**1**,**2. In: Journal of the American Chemical Society. 1983 ; Vol. 105, No. 25. pp. 7252-7255.
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