Conduction system injury after aortic valve dilation in the dog single- versus double-balloon catheters

R. H. Plack, G. M. Hutchins, Jeffrey A Brinker

Research output: Contribution to journalArticle

Abstract

The range of morbidity induced by valvuloplasty is not fully known, but transient conduction disturbances are common. The authors performed aortic valve balloon dilatation on 10 closed-chest dogs with normal aortic valves, using a femoral cutdown approach and fluoroscopic guidance. Four were done with a single 15 mm balloon catheter, and in the other 6 two 12 mm balloon catheters were used. Balloons were inflated to 5 to 12 atms pressure with contrast solution. After several inflations the dogs were sacrificed, the hearts removed and examined. Gross examination revealed subendocardial hemorrhage in the outflow tract in 5 of the 6 in which double balloons had been used. Microscopically, all aortic valve areas showed hemorrahage, mostly in loose connective tissues of the valve leaflets. The severity of injury appeared greater when two ballons had been used. Histologic examination showed definite injury to the myocytes of the left bundle branch in all 6 of the double-ballooned dogs, but in none of those subjected to the single-balloon procedure. During aortic valve dilation the only manifestation of conduction system injury was prolongation of the QRS complex in 3 of the 6 dogs in which a double-balloon catheter had been used. The results suggest that electrocardiographic conduction disturbances observed in patients undergoing aortic valvuloplasty may be the result of direct injury of conduction tissue and may be more likely to occur when larger balloons are used.

Original languageEnglish (US)
Pages (from-to)929-935
Number of pages7
JournalAngiology
Volume41
Issue number11
StatePublished - 1990

Fingerprint

Aortic Valve
Dilatation
Catheters
Dogs
Wounds and Injuries
Economic Inflation
Thigh
Connective Tissue
Muscle Cells
Thorax
Hemorrhage
Morbidity
Pressure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Conduction system injury after aortic valve dilation in the dog single- versus double-balloon catheters. / Plack, R. H.; Hutchins, G. M.; Brinker, Jeffrey A.

In: Angiology, Vol. 41, No. 11, 1990, p. 929-935.

Research output: Contribution to journalArticle

@article{442ed8c47bac4434a060fac06e160e93,
title = "Conduction system injury after aortic valve dilation in the dog single- versus double-balloon catheters",
abstract = "The range of morbidity induced by valvuloplasty is not fully known, but transient conduction disturbances are common. The authors performed aortic valve balloon dilatation on 10 closed-chest dogs with normal aortic valves, using a femoral cutdown approach and fluoroscopic guidance. Four were done with a single 15 mm balloon catheter, and in the other 6 two 12 mm balloon catheters were used. Balloons were inflated to 5 to 12 atms pressure with contrast solution. After several inflations the dogs were sacrificed, the hearts removed and examined. Gross examination revealed subendocardial hemorrhage in the outflow tract in 5 of the 6 in which double balloons had been used. Microscopically, all aortic valve areas showed hemorrahage, mostly in loose connective tissues of the valve leaflets. The severity of injury appeared greater when two ballons had been used. Histologic examination showed definite injury to the myocytes of the left bundle branch in all 6 of the double-ballooned dogs, but in none of those subjected to the single-balloon procedure. During aortic valve dilation the only manifestation of conduction system injury was prolongation of the QRS complex in 3 of the 6 dogs in which a double-balloon catheter had been used. The results suggest that electrocardiographic conduction disturbances observed in patients undergoing aortic valvuloplasty may be the result of direct injury of conduction tissue and may be more likely to occur when larger balloons are used.",
author = "Plack, {R. H.} and Hutchins, {G. M.} and Brinker, {Jeffrey A}",
year = "1990",
language = "English (US)",
volume = "41",
pages = "929--935",
journal = "Angiology",
issn = "0003-3197",
publisher = "SAGE Publications Inc.",
number = "11",

}

TY - JOUR

T1 - Conduction system injury after aortic valve dilation in the dog single- versus double-balloon catheters

AU - Plack, R. H.

AU - Hutchins, G. M.

AU - Brinker, Jeffrey A

PY - 1990

Y1 - 1990

N2 - The range of morbidity induced by valvuloplasty is not fully known, but transient conduction disturbances are common. The authors performed aortic valve balloon dilatation on 10 closed-chest dogs with normal aortic valves, using a femoral cutdown approach and fluoroscopic guidance. Four were done with a single 15 mm balloon catheter, and in the other 6 two 12 mm balloon catheters were used. Balloons were inflated to 5 to 12 atms pressure with contrast solution. After several inflations the dogs were sacrificed, the hearts removed and examined. Gross examination revealed subendocardial hemorrhage in the outflow tract in 5 of the 6 in which double balloons had been used. Microscopically, all aortic valve areas showed hemorrahage, mostly in loose connective tissues of the valve leaflets. The severity of injury appeared greater when two ballons had been used. Histologic examination showed definite injury to the myocytes of the left bundle branch in all 6 of the double-ballooned dogs, but in none of those subjected to the single-balloon procedure. During aortic valve dilation the only manifestation of conduction system injury was prolongation of the QRS complex in 3 of the 6 dogs in which a double-balloon catheter had been used. The results suggest that electrocardiographic conduction disturbances observed in patients undergoing aortic valvuloplasty may be the result of direct injury of conduction tissue and may be more likely to occur when larger balloons are used.

AB - The range of morbidity induced by valvuloplasty is not fully known, but transient conduction disturbances are common. The authors performed aortic valve balloon dilatation on 10 closed-chest dogs with normal aortic valves, using a femoral cutdown approach and fluoroscopic guidance. Four were done with a single 15 mm balloon catheter, and in the other 6 two 12 mm balloon catheters were used. Balloons were inflated to 5 to 12 atms pressure with contrast solution. After several inflations the dogs were sacrificed, the hearts removed and examined. Gross examination revealed subendocardial hemorrhage in the outflow tract in 5 of the 6 in which double balloons had been used. Microscopically, all aortic valve areas showed hemorrahage, mostly in loose connective tissues of the valve leaflets. The severity of injury appeared greater when two ballons had been used. Histologic examination showed definite injury to the myocytes of the left bundle branch in all 6 of the double-ballooned dogs, but in none of those subjected to the single-balloon procedure. During aortic valve dilation the only manifestation of conduction system injury was prolongation of the QRS complex in 3 of the 6 dogs in which a double-balloon catheter had been used. The results suggest that electrocardiographic conduction disturbances observed in patients undergoing aortic valvuloplasty may be the result of direct injury of conduction tissue and may be more likely to occur when larger balloons are used.

UR - http://www.scopus.com/inward/record.url?scp=0025609320&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025609320&partnerID=8YFLogxK

M3 - Article

C2 - 2244697

AN - SCOPUS:0025609320

VL - 41

SP - 929

EP - 935

JO - Angiology

JF - Angiology

SN - 0003-3197

IS - 11

ER -