Abstract
We report a 1-year-old female child presenting with hypereosinophilia who was found to have concurrent myeloid sarcoma and a central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT). She was later found to have a germline mutation in SMARCB1. Concurrent hematologic malignancy and CNS AT/RT have not previously been described in the context of a SMARCB1 loss-of-function germline mutation.
Original language | English (US) |
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Article number | e26460 |
Journal | Pediatric Blood and Cancer |
Volume | 64 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2017 |
Keywords
- SMARCB1
- brain tumors
- eosinophilia
- myeloid sarcoma
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology