Concomitant doxorubicin and irradiation for additive cytotoxicity in adrenocortical carcinoma

D. W. Orr, S. E. Order, D. S. Ettinger

Research output: Contribution to journalArticle

Abstract

The advantages of multimodality therapy are clearly illustrated in this patient with metastatic anaplastic adrenocortical carcinoma, complicated by myasthenia gravis, and treated with chemotherapy, radiotherapy, and surgery. The concomitant administration of doxorubicin and radiotherapy resulted in marked tumor reduction followed by resection of a solitary pulmonary metastasis and definitive local surgery. A detailed review of the cytotoxic actions of doxorubicin and irradiation provides the background of the authors' rationale for this therapeutic combination.

Original languageEnglish (US)
Pages (from-to)250-262
Number of pages13
JournalMedical Grand Rounds
Volume3
Issue number3
StatePublished - Dec 1 1984

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Concomitant doxorubicin and irradiation for additive cytotoxicity in adrenocortical carcinoma'. Together they form a unique fingerprint.

  • Cite this