Concentrations of erythromycin in serum and tonsil: comparison of the estolate and ethyl succinate suspensions

Paul S. Lietman, Charles M. Ginsburg, George H. McCracken, M. C. Culbertson

Research output: Contribution to journalArticle


Concentrations of erythromycin were measured in serum and tonsil from children who had received either the estolate or ethyl succinate suspension before surgery. The in vitro assay measured total erythromycin activity against a group A beta hemolytic streptococcus. Levels of erythromycin in serum and tonsil after single and multiple doses of the estolate were significantly higher than those after administration of the ethyl succinate. The therapeutic implications of these findings are unknown.

Original languageEnglish (US)
Pages (from-to)1011-1013
Number of pages3
JournalThe Journal of pediatrics
Issue number6
StatePublished - Dec 1976


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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