TY - JOUR
T1 - Concentration of lead, mercury, cadmium, aluminum, arsenic and manganese in umbilical cord blood of Jamaican newborns
AU - Rahbar, Mohammad H.
AU - Samms-Vaughan, Maureen
AU - Dickerson, Aisha S.
AU - Hessabi, Manouchehr
AU - Bressler, Jan
AU - Desai, Charlene Coore
AU - Shakespeare-Pellington, Sydonnie
AU - Reece, Jody Ann
AU - Morgan, Renee
AU - Loveland, Katherine A.
AU - Grove, Megan L.
AU - Boerwinkle, Eric
N1 - Publisher Copyright:
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
PY - 2015/4/23
Y1 - 2015/4/23
N2 - The objective of this study was to characterize the concentrations of lead, mercury, cadmium, aluminum, and manganese in umbilical cord blood of Jamaican newborns and to explore the possible association between concentrations of these elements and certain birth outcomes. Based on data from 100 pregnant mothers and their 100 newborns who were enrolled from Jamaica in 2011, the arithmetic mean (standard deviation) concentrations of cord blood lead, mercury, aluminum, and manganese were 0.8 (1.3 μg/dL), 4.4 (2.4 μg/L), 10.9 (9.2 μg/L), and 43.7 (17.7 μg/L), respectively. In univariable General Linear Models, the geometric mean cord blood aluminum concentration was higher for children whose mothers had completed their education up to high school compared to those whose mothers had any education beyond high school (12.2 μg/L vs. 6.4 μg/L; p < 0.01). After controlling for maternal education level and socioeconomic status (through ownership of a family car), the cord blood lead concentration was significantly associated with head circumference (adjusted p < 0.01). Our results not only provide levels of arsenic and the aforementioned metals in cord blood that could serve as a reference for the Jamaican population, but also replicate previously reported significant associations between cord blood lead concentrations and head circumference at birth in other populations.
AB - The objective of this study was to characterize the concentrations of lead, mercury, cadmium, aluminum, and manganese in umbilical cord blood of Jamaican newborns and to explore the possible association between concentrations of these elements and certain birth outcomes. Based on data from 100 pregnant mothers and their 100 newborns who were enrolled from Jamaica in 2011, the arithmetic mean (standard deviation) concentrations of cord blood lead, mercury, aluminum, and manganese were 0.8 (1.3 μg/dL), 4.4 (2.4 μg/L), 10.9 (9.2 μg/L), and 43.7 (17.7 μg/L), respectively. In univariable General Linear Models, the geometric mean cord blood aluminum concentration was higher for children whose mothers had completed their education up to high school compared to those whose mothers had any education beyond high school (12.2 μg/L vs. 6.4 μg/L; p < 0.01). After controlling for maternal education level and socioeconomic status (through ownership of a family car), the cord blood lead concentration was significantly associated with head circumference (adjusted p < 0.01). Our results not only provide levels of arsenic and the aforementioned metals in cord blood that could serve as a reference for the Jamaican population, but also replicate previously reported significant associations between cord blood lead concentrations and head circumference at birth in other populations.
KW - Aluminum
KW - Arsenic
KW - Cadmium
KW - Cord blood
KW - Jamaica
KW - Lead
KW - Manganese
KW - Mercury
KW - Newborns
UR - http://www.scopus.com/inward/record.url?scp=84929378731&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929378731&partnerID=8YFLogxK
U2 - 10.3390/ijerph120504481
DO - 10.3390/ijerph120504481
M3 - Article
C2 - 25915835
AN - SCOPUS:84929378731
VL - 12
SP - 4481
EP - 4501
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
SN - 1661-7827
IS - 5
ER -