Computer ranking of the sequence of appearance of 40 features of the brain and related structures in staged human embryos during the seventh week of development

R. O'Rahilly, F. Muller, G. W. Hutchins, G. M. Moore

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The sequence of events in the development of the brain in human embryos, already published for stages 8-17, is here continued for stages 18 and 19. with the aid of a computerized bubble-sort algorithm, 58 individual embryos were ranked in ascending order of the features present. the increasing structural complexity provided 40 new features in these two stages. the chief characteristics of stage 18 (approximately 44 postovulatory days) are rapidly growing basal nuclei; appearance of the extraventricular bulge of the cerebellum (flocculus), of the superior cerebellar peduncle, and of follicles in the epiphysis cerebri; and the presence of vomeronasal organ and ganglion, of the bucconasal membrane, and of isolated semicircular ducts. The main features of stage 19 (approximately 48 days) are the cochlear nuclei, the ganglion of the nervus terminalis, nuclei of the prosencephalic septum, the appearance of the subcommissural organ, the presence of villi in the choroid plexuses of the fourth and lateral ventricles, and the stria medullaris thalami.

    Original languageEnglish (US)
    Pages (from-to)295-317
    Number of pages23
    JournalAmerican Journal of Anatomy
    Volume182
    Issue number4
    StatePublished - 1988

    ASJC Scopus subject areas

    • Anatomy

    Fingerprint Dive into the research topics of 'Computer ranking of the sequence of appearance of 40 features of the brain and related structures in staged human embryos during the seventh week of development'. Together they form a unique fingerprint.

    Cite this