TY - GEN
T1 - Computer models of the heart
T2 - 2nd IEEE International Conference on Information Technology Applications in Biomedicine, ITAB 1998
AU - Thakor, Nitish V.
N1 - Funding Information:
Several students contributed over many years to carry out this work. I acknowledge in particular the efforts of Rose Province and Matthew Fishler. The work reported here was supported by several awards including NIH Research Career and the NSF Presidential Young Investigator Awards.
Publisher Copyright:
© 1998 IEEE.
PY - 1998
Y1 - 1998
N2 - Supercomputers have greatly influenced the studies of biological cells and cellular networks. Electrophysiological properties of the cells are now known in great detail. Therefore, computer models are constructed to simulate the electrical activity of single heart cells and networks of coupled heart cells. These simulations are used to mimic the rhythms of the heart, including arrhythmias such as ventricular fibrillation (VF). Computer simulations require very large scale computational resources, with parallel or vector architectures offering distinct benefits in terms of the ease of coding the algorithms and in terms of computational performance. Three models, one implemented on a personal computer, the second on a Connection Machine and the third on a Cray C90, are reported. The computer simulations reveal the mechanism of generation of VF-like rhythms in the form of wavelets and spiral waves and suggest novel strategies for terminating these arrhythmias.
AB - Supercomputers have greatly influenced the studies of biological cells and cellular networks. Electrophysiological properties of the cells are now known in great detail. Therefore, computer models are constructed to simulate the electrical activity of single heart cells and networks of coupled heart cells. These simulations are used to mimic the rhythms of the heart, including arrhythmias such as ventricular fibrillation (VF). Computer simulations require very large scale computational resources, with parallel or vector architectures offering distinct benefits in terms of the ease of coding the algorithms and in terms of computational performance. Three models, one implemented on a personal computer, the second on a Connection Machine and the third on a Cray C90, are reported. The computer simulations reveal the mechanism of generation of VF-like rhythms in the form of wavelets and spiral waves and suggest novel strategies for terminating these arrhythmias.
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U2 - 10.1109/ITAB.1998.674668
DO - 10.1109/ITAB.1998.674668
M3 - Conference contribution
AN - SCOPUS:85054404803
SN - 0780349733
SN - 9780780349735
T3 - Proceedings - 1998 IEEE International Conference on Information Technology Applications in Biomedicine, ITAB 1998
SP - 35
EP - 39
BT - Proceedings - 1998 IEEE International Conference on Information Technology Applications in Biomedicine, ITAB 1998
A2 - Micheli-Tzanakou, Evangelia
A2 - Laxminarayan, Swamy
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 16 May 1998 through 17 May 1998
ER -