Computer-assisted analysis of regulation of the glycerol-3-phosphate metabolism in genomes of proteobacteria

L. V. Danilova, M. S. Gelfand, V. A. Lyubetsky, O. N. Laikova

Research output: Contribution to journalArticlepeer-review

Abstract

Comparative computer-assisted analysis was used to study putative GlpR-regulons responsible for metabolism of glycerol and glycerol-3-phosphate in genomes of α-, β-, and γ-proteobacteria. New palindromic GlpR-binding signals were identified in γ-proteobacteria; consensus sequences being TGTTCGATAACGAACA for Enterobacteriaceae, wTTTTCGTATACGAAAAw for Pseudomonadaceae, and AATGCTCGATCGAGCATT for Vibrionaceae. The signals in α- and β-proteobacteria were also identified: they contained 3-4 direct TTTCGTT repeats separated by 3-4 nucleotide pairs.

Original languageEnglish (US)
Pages (from-to)843-849
Number of pages7
JournalMolekulyarnaya Biologiya
Volume37
Issue number5
StatePublished - Dec 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Computer-assisted analysis of regulation of the glycerol-3-phosphate metabolism in genomes of proteobacteria'. Together they form a unique fingerprint.

Cite this