Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma

A prospective comparison

P. O. Alderson, D. F. Adams, B. J. McNeil, R. Sanders, S. S. Siegelman, H. J. Finberg, S. J. Hessel, H. L. Abrams

Research output: Contribution to journalArticle

Abstract

A prospective evaluation of computed tomography (CT), ultrasonography (US), and Tc-99m sulfur colloid scintigraphy of the liver was performed in 189 patients who had either colon (n = 129) or breast (n = 60) carcinoma. Imaging was performed with fourth-generation CT scanners, gray-scale or phased array ultrasound scanners, and 37-tube gamma cameras. Studies were evaluated independently and receiver operating characteristic (ROC) curves were constructed. In addition, a standard 2 x 2 matrix analysis was performed. In patients who had all three examinations (n = 122), the matrix analysis showed that CT had a slightly higher sensitivity (0.93) than scintigraphy (0.86) or US (0.82); specificities were 0.88, 0.83, and 0.85, respectively. These differences were not statistically significant. However, ROC curves showed that CT had the highest true-positive ratio at every false-positive ratio, and that US had the lowest. The performance of CT did not differ significantly from that of scintigraphy, but was better than that of US (p <.05), especially in patients with breast carcinoma. Overall, CT provided the most accurate means for detecting liver metastases from both primary lesions.

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalRadiology
Volume149
Issue number1
StatePublished - 1983
Externally publishedYes

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Radionuclide Imaging
Colon
Tomography
Breast Neoplasms
Ultrasonography
Liver
ROC Curve
Technetium Tc 99m Sulfur Colloid
X-Ray Computed Tomography Scanners
Gamma Cameras
Breast
Neoplasm Metastasis
Carcinoma

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Alderson, P. O., Adams, D. F., McNeil, B. J., Sanders, R., Siegelman, S. S., Finberg, H. J., ... Abrams, H. L. (1983). Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma: A prospective comparison. Radiology, 149(1), 225-230.

Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma : A prospective comparison. / Alderson, P. O.; Adams, D. F.; McNeil, B. J.; Sanders, R.; Siegelman, S. S.; Finberg, H. J.; Hessel, S. J.; Abrams, H. L.

In: Radiology, Vol. 149, No. 1, 1983, p. 225-230.

Research output: Contribution to journalArticle

Alderson, PO, Adams, DF, McNeil, BJ, Sanders, R, Siegelman, SS, Finberg, HJ, Hessel, SJ & Abrams, HL 1983, 'Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma: A prospective comparison', Radiology, vol. 149, no. 1, pp. 225-230.
Alderson PO, Adams DF, McNeil BJ, Sanders R, Siegelman SS, Finberg HJ et al. Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma: A prospective comparison. Radiology. 1983;149(1):225-230.
Alderson, P. O. ; Adams, D. F. ; McNeil, B. J. ; Sanders, R. ; Siegelman, S. S. ; Finberg, H. J. ; Hessel, S. J. ; Abrams, H. L. / Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma : A prospective comparison. In: Radiology. 1983 ; Vol. 149, No. 1. pp. 225-230.
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