Computed tomography of the spleen and liver in sickle cell disease

D. Magid, E. K. Fishman, S. S. Siegelman

Research output: Contribution to journalArticlepeer-review


The spleen was assessed in 10 patients with sickle cell disease studied with computed tomography (CT) for abdominal pain and/or unexplained fever. Patients with homozygous sickle cell anemia were found to have small, densely calcified spleens with occasional low-density infarcts. Five of six had hepatomegaly, and there was one case each of hepatic abscess, infarcts, and hemochromatosis. All patients with heterozygous sickle cell disease were found to have splenomegaly, with a variety of findings including acute hemorrhage, acute and chronic infarcts, rupture, and possible sequestration. It was concluded that CT is useful for evaluating the status of the spleen and liver in symptomatic patients with sickle cell disease.

Original languageEnglish (US)
Pages (from-to)245-249
Number of pages5
JournalAmerican Journal of Roentgenology
Issue number2
StatePublished - 1984

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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