Computational analysis of ChIP-seq data.

Research output: Contribution to journalArticle

Abstract

Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein-DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein-DNA interactions from ChIP-seq experiments.

Original languageEnglish (US)
Pages (from-to)143-159
Number of pages17
JournalMethods in molecular biology (Clifton, N.J.)
Volume674
StatePublished - 2010

Fingerprint

Genome
Protein Interaction Maps
High-Throughput Nucleotide Sequencing
Chromatin Immunoprecipitation
DNA
Chromatin
Transcription Factors
Binding Sites
Technology
Genes
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Computational analysis of ChIP-seq data. / Ji, Hong Kai.

In: Methods in molecular biology (Clifton, N.J.), Vol. 674, 2010, p. 143-159.

Research output: Contribution to journalArticle

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