Computational analysis of ChIP-seq data.

Research output: Contribution to journalArticle

Abstract

Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein-DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein-DNA interactions from ChIP-seq experiments.

Original languageEnglish (US)
Pages (from-to)143-159
Number of pages17
JournalMethods in molecular biology (Clifton, N.J.)
Volume674
DOIs
StatePublished - 2010

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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