Comprehensive resource: Skeletal gene database

Libin Jia, Nicola C. Ho, Susan S. Park, John Powell, Clair Ann Francomano

Research output: Contribution to journalArticle

Abstract

The Skeletal Gene Database (SGD) is an integrated resource that provides comprehensive information about bone-related genes, mRNA, and proteins expressed in human and mouse, with rich links to numerous other electronic tools. SGD contains expressed sequence tag (EST) data from all the skeletal-related cDNA libraries that are available to the public. It supplies the query/data access analytic tools for users to search and compare each gene expressed in skeletal tissue(s). The results derived from EST tissue expression profiling will allow users to get the data on the mRNA copy numbers of each gene expressed in each tissue and its normalized value. From the SGD, researchers can obtain information regarding the name, symbol, size, exon/intron number, chromosomal location, LocusLink, and related disease (if any is known) of each gene. This electronic compendium also furnishes information on the protein of the corresponding gene including the protein size (amino acid number and molecular weight). It provides swift and ready access to other useful databases including OMIM, UniGene and PUBMED. The data will be updated regularly in step with current and future research, thereby providing what we hope will serve as a highly useful source of information and a powerful analytic tool to the scientific community. Published 2002 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)275-281
Number of pages7
JournalAmerican Journal of Medical Genetics - Seminars in Medical Genetics
Volume106
Issue number4
DOIs
StatePublished - 2002

Fingerprint

Databases
Genes
Expressed Sequence Tags
Genetic Databases
Messenger RNA
Proteins
Gene Dosage
Gene Library
Introns
Names
Exons
Molecular Weight
Research Personnel
Amino Acids
Bone and Bones

Keywords

  • Data mining
  • Gene expression analysis
  • Skeletal gene database

ASJC Scopus subject areas

  • Genetics(clinical)
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)

Cite this

Comprehensive resource : Skeletal gene database. / Jia, Libin; Ho, Nicola C.; Park, Susan S.; Powell, John; Francomano, Clair Ann.

In: American Journal of Medical Genetics - Seminars in Medical Genetics, Vol. 106, No. 4, 2002, p. 275-281.

Research output: Contribution to journalArticle

Jia, Libin ; Ho, Nicola C. ; Park, Susan S. ; Powell, John ; Francomano, Clair Ann. / Comprehensive resource : Skeletal gene database. In: American Journal of Medical Genetics - Seminars in Medical Genetics. 2002 ; Vol. 106, No. 4. pp. 275-281.
@article{14419c3d6524409a8cdd0f60bb44d805,
title = "Comprehensive resource: Skeletal gene database",
abstract = "The Skeletal Gene Database (SGD) is an integrated resource that provides comprehensive information about bone-related genes, mRNA, and proteins expressed in human and mouse, with rich links to numerous other electronic tools. SGD contains expressed sequence tag (EST) data from all the skeletal-related cDNA libraries that are available to the public. It supplies the query/data access analytic tools for users to search and compare each gene expressed in skeletal tissue(s). The results derived from EST tissue expression profiling will allow users to get the data on the mRNA copy numbers of each gene expressed in each tissue and its normalized value. From the SGD, researchers can obtain information regarding the name, symbol, size, exon/intron number, chromosomal location, LocusLink, and related disease (if any is known) of each gene. This electronic compendium also furnishes information on the protein of the corresponding gene including the protein size (amino acid number and molecular weight). It provides swift and ready access to other useful databases including OMIM, UniGene and PUBMED. The data will be updated regularly in step with current and future research, thereby providing what we hope will serve as a highly useful source of information and a powerful analytic tool to the scientific community. Published 2002 Wiley-Liss, Inc.",
keywords = "Data mining, Gene expression analysis, Skeletal gene database",
author = "Libin Jia and Ho, {Nicola C.} and Park, {Susan S.} and John Powell and Francomano, {Clair Ann}",
year = "2002",
doi = "10.1002/ajmg.10227",
language = "English (US)",
volume = "106",
pages = "275--281",
journal = "American Journal of Medical Genetics, Part A",
issn = "1552-4825",
publisher = "Wiley-Liss Inc.",
number = "4",

}

TY - JOUR

T1 - Comprehensive resource

T2 - Skeletal gene database

AU - Jia, Libin

AU - Ho, Nicola C.

AU - Park, Susan S.

AU - Powell, John

AU - Francomano, Clair Ann

PY - 2002

Y1 - 2002

N2 - The Skeletal Gene Database (SGD) is an integrated resource that provides comprehensive information about bone-related genes, mRNA, and proteins expressed in human and mouse, with rich links to numerous other electronic tools. SGD contains expressed sequence tag (EST) data from all the skeletal-related cDNA libraries that are available to the public. It supplies the query/data access analytic tools for users to search and compare each gene expressed in skeletal tissue(s). The results derived from EST tissue expression profiling will allow users to get the data on the mRNA copy numbers of each gene expressed in each tissue and its normalized value. From the SGD, researchers can obtain information regarding the name, symbol, size, exon/intron number, chromosomal location, LocusLink, and related disease (if any is known) of each gene. This electronic compendium also furnishes information on the protein of the corresponding gene including the protein size (amino acid number and molecular weight). It provides swift and ready access to other useful databases including OMIM, UniGene and PUBMED. The data will be updated regularly in step with current and future research, thereby providing what we hope will serve as a highly useful source of information and a powerful analytic tool to the scientific community. Published 2002 Wiley-Liss, Inc.

AB - The Skeletal Gene Database (SGD) is an integrated resource that provides comprehensive information about bone-related genes, mRNA, and proteins expressed in human and mouse, with rich links to numerous other electronic tools. SGD contains expressed sequence tag (EST) data from all the skeletal-related cDNA libraries that are available to the public. It supplies the query/data access analytic tools for users to search and compare each gene expressed in skeletal tissue(s). The results derived from EST tissue expression profiling will allow users to get the data on the mRNA copy numbers of each gene expressed in each tissue and its normalized value. From the SGD, researchers can obtain information regarding the name, symbol, size, exon/intron number, chromosomal location, LocusLink, and related disease (if any is known) of each gene. This electronic compendium also furnishes information on the protein of the corresponding gene including the protein size (amino acid number and molecular weight). It provides swift and ready access to other useful databases including OMIM, UniGene and PUBMED. The data will be updated regularly in step with current and future research, thereby providing what we hope will serve as a highly useful source of information and a powerful analytic tool to the scientific community. Published 2002 Wiley-Liss, Inc.

KW - Data mining

KW - Gene expression analysis

KW - Skeletal gene database

UR - http://www.scopus.com/inward/record.url?scp=0036165694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036165694&partnerID=8YFLogxK

U2 - 10.1002/ajmg.10227

DO - 10.1002/ajmg.10227

M3 - Article

C2 - 11891679

AN - SCOPUS:0036165694

VL - 106

SP - 275

EP - 281

JO - American Journal of Medical Genetics, Part A

JF - American Journal of Medical Genetics, Part A

SN - 1552-4825

IS - 4

ER -