Composite tissue allotransplantation - A new era in plastic surgery?

Shehan Hettiaratchy, Mark A. Randolph, Fraņcois Petit, W P Andrew Lee, Peter E M Butler

Research output: Contribution to journalArticle

Abstract

Composite tissue allotransplantation (CTA) holds great potential for reconstructive surgery. The recent hand transplants have made this a clinical reality. However, concerns about CTA have divided the medical community. The current transplants require life-long immunosuppression, which could place the recipients at risk of serious complications. In addition despite potent immunosuppression, chronic rejection may still negate any early favourable results. This article will outline the clinical experience of CTA, the major problems of the technique and the potential solutions to these problems.

Original languageEnglish (US)
Pages (from-to)381-391
Number of pages11
JournalBritish Journal of Plastic Surgery
Volume57
Issue number5
DOIs
StatePublished - Jul 2004
Externally publishedYes

Fingerprint

Vascularized Composite Allotransplantation
Plastic Surgery
Immunosuppression
Reconstructive Surgical Procedures
Transplants
Hand

Keywords

  • Composite tissue transplantation
  • Immunosuppression
  • Tolerance

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

Hettiaratchy, S., Randolph, M. A., Petit, F., Lee, W. P. A., & Butler, P. E. M. (2004). Composite tissue allotransplantation - A new era in plastic surgery? British Journal of Plastic Surgery, 57(5), 381-391. https://doi.org/10.1016/j.bjps.2004.02.012

Composite tissue allotransplantation - A new era in plastic surgery? / Hettiaratchy, Shehan; Randolph, Mark A.; Petit, Fraņcois; Lee, W P Andrew; Butler, Peter E M.

In: British Journal of Plastic Surgery, Vol. 57, No. 5, 07.2004, p. 381-391.

Research output: Contribution to journalArticle

Hettiaratchy, S, Randolph, MA, Petit, F, Lee, WPA & Butler, PEM 2004, 'Composite tissue allotransplantation - A new era in plastic surgery?', British Journal of Plastic Surgery, vol. 57, no. 5, pp. 381-391. https://doi.org/10.1016/j.bjps.2004.02.012
Hettiaratchy, Shehan ; Randolph, Mark A. ; Petit, Fraņcois ; Lee, W P Andrew ; Butler, Peter E M. / Composite tissue allotransplantation - A new era in plastic surgery?. In: British Journal of Plastic Surgery. 2004 ; Vol. 57, No. 5. pp. 381-391.
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