TY - JOUR
T1 - Complications of Uveitis
T2 - The Northern California Epidemiology of Uveitis Study
AU - Gritz, David
AU - Schwaber, Eric J.
AU - Wong, Ira G.
PY - 2017/1/23
Y1 - 2017/1/23
N2 - Purpose: To describe the uveitis complications in a large, community-based cohort. Methods: Retrospective, community-based, cross-sectional cohort study analyzing complications and associations with complications. Results: A total of 844 cases of uveitis were found; 342 were new-onset, and 462 were prior-onset. In total, 29.5% of patients were affected by one or more complications associated with age, gender, course, and anatomic location of uveitis. Visual loss was experienced by 19.1% of patients and was associated with age, course of disease, and anatomic location of uveitis. Of the patients who developed glaucoma or elevated intraocular pressure over 30 mmHg, 3.9% (n = 33) were related solely to uveitis; 5.2% (n = 44) had an unclear or combined mechanism; and 1.8% (n = 15) were related solely to steroid response. Cystoid macular edema was associated with course of disease and anatomic location of uveitis. Conclusions: Complications affect a significant portion of uveitis patients, and are often associated with demographic and clinical factors.
AB - Purpose: To describe the uveitis complications in a large, community-based cohort. Methods: Retrospective, community-based, cross-sectional cohort study analyzing complications and associations with complications. Results: A total of 844 cases of uveitis were found; 342 were new-onset, and 462 were prior-onset. In total, 29.5% of patients were affected by one or more complications associated with age, gender, course, and anatomic location of uveitis. Visual loss was experienced by 19.1% of patients and was associated with age, course of disease, and anatomic location of uveitis. Of the patients who developed glaucoma or elevated intraocular pressure over 30 mmHg, 3.9% (n = 33) were related solely to uveitis; 5.2% (n = 44) had an unclear or combined mechanism; and 1.8% (n = 15) were related solely to steroid response. Cystoid macular edema was associated with course of disease and anatomic location of uveitis. Conclusions: Complications affect a significant portion of uveitis patients, and are often associated with demographic and clinical factors.
KW - Complications
KW - epidemiology
KW - glaucoma
KW - steroid-response
KW - uveitis
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U2 - 10.1080/09273948.2016.1247174
DO - 10.1080/09273948.2016.1247174
M3 - Article
C2 - 28112975
AN - SCOPUS:85010653966
SP - 1
EP - 11
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
SN - 0927-3948
ER -