Complications in using automated methods to increase clinical trial accrual

Sergiy Fefilatyev; Li Chen; Tim V. Ivanovskiy; Lawrence O. Hall; Dmitry B. Goldgof; Halina Greenstien; Christopher R. Garrett

doi:10.1504/IJBET.2010.034519

Complications in using automated methods to increase clinical trial accrual

Sergiy Fefilatyev, Li Chen, Tim V. Ivanovskiy, Lawrence O. Hall, Dmitry B. Goldgof, Halina Greenstien, Christopher R. Garrett

Research output: Contribution to journal › Article › peer-review

Abstract

This paper describes the issues involved in improving accruals for clinical trials using a web-based system. We installed a custom web-based expert system at the H. Lee Moffitt Cancer Center and Research Institute to help physicians screen patients for phase II clinical trials. The system allows physicians to screen a patient for multiple trials simultaneously. Experiments have shown that adaptation of the system into a clinical environment and the success of the system are related to the amount of time physicians are willing to spend entering data. We also found significant regulatory issues (HIPAA) that make implementation challenging.

Original language	English (US)
Pages (from-to)	134-150
Number of pages	17
Journal	International Journal of Biomedical Engineering and Technology
Volume	4
Issue number	2
DOIs	https://doi.org/10.1504/IJBET.2010.034519
State	Published - Aug 2010
Externally published	Yes

Keywords

Clinical trial acrual
Cost
Difficulties
Expert system

ASJC Scopus subject areas

Biomedical Engineering

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10.1504/IJBET.2010.034519

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AU - Greenstien, Halina

AU - Garrett, Christopher R.

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AB - This paper describes the issues involved in improving accruals for clinical trials using a web-based system. We installed a custom web-based expert system at the H. Lee Moffitt Cancer Center and Research Institute to help physicians screen patients for phase II clinical trials. The system allows physicians to screen a patient for multiple trials simultaneously. Experiments have shown that adaptation of the system into a clinical environment and the success of the system are related to the amount of time physicians are willing to spend entering data. We also found significant regulatory issues (HIPAA) that make implementation challenging.

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Complications in using automated methods to increase clinical trial accrual

Abstract

Keywords

ASJC Scopus subject areas

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