Complex partial seizures and mesial temporal sclerosis: Evaluation with fast spin-echo MR imaging

Robert D. Tien; Gary J. Felsberg; Claudio Campi De Castro; Alan K. Osumi; Darrell V. Lewis; Alan H. Friedman; Barbara Crain; Rodney A. Radtke

doi:10.1148/radiology.189.3.8234712

Complex partial seizures and mesial temporal sclerosis: Evaluation with fast spin-echo MR imaging

Robert D. Tien, Gary J. Felsberg, Claudio Campi De Castro, Alan K. Osumi, Darrell V. Lewis, Alan H. Friedman, Barbara Crain, Rodney A. Radtke

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

PURPOSE: This study was performed to determine the sensitivity and specificity of fast spin-echo (FSE) magnetic resonance (MR) imaging in detecting mesial temporal sclerosis. MATERIALS AND METHODS: Twenty-one patients with a diagnosis of complex partial seizures were studied. Criteria for abnormality included visual detection of hippocampal MR signal abnormality and atrophy or significantly decreased hippocampal volume determined by using MR morphometric techniques. RESULTS: The overall sensitivity and specificity of MR imaging in demonstrating correct lateralization of seizure focus were both 100%. The positive predictive value of FSE MR imaging was 100%. The negative predictive value was 50%. CONCLUSION: The authors recommend FSE MR imaging of the hippocampus as the imaging technique of choice in the evaluation of patients with complex partial seizures for mesial temporal sclerosis.

Original language	English (US)
Pages (from-to)	835-842
Number of pages	8
Journal	RADIOLOGY
Volume	189
Issue number	3
DOIs	https://doi.org/10.1148/radiology.189.3.8234712
State	Published - Dec 1993
Externally published	Yes

Keywords

Brain, abnormalities, 1341.142, 1341.83
Epilepsy
Magnetic resonance (MR), thin-section, 1341.121411, 1341.121416

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1148/radiology.189.3.8234712

Cite this

@article{d86a0f6bce1b487b9066633621eccd02,

title = "Complex partial seizures and mesial temporal sclerosis: Evaluation with fast spin-echo MR imaging",

abstract = "PURPOSE: This study was performed to determine the sensitivity and specificity of fast spin-echo (FSE) magnetic resonance (MR) imaging in detecting mesial temporal sclerosis. MATERIALS AND METHODS: Twenty-one patients with a diagnosis of complex partial seizures were studied. Criteria for abnormality included visual detection of hippocampal MR signal abnormality and atrophy or significantly decreased hippocampal volume determined by using MR morphometric techniques. RESULTS: The overall sensitivity and specificity of MR imaging in demonstrating correct lateralization of seizure focus were both 100%. The positive predictive value of FSE MR imaging was 100%. The negative predictive value was 50%. CONCLUSION: The authors recommend FSE MR imaging of the hippocampus as the imaging technique of choice in the evaluation of patients with complex partial seizures for mesial temporal sclerosis.",

keywords = "Brain, abnormalities, 1341.142, 1341.83, Epilepsy, Magnetic resonance (MR), thin-section, 1341.121411, 1341.121416",

author = "Tien, {Robert D.} and Felsberg, {Gary J.} and {De Castro}, {Claudio Campi} and Osumi, {Alan K.} and Lewis, {Darrell V.} and Friedman, {Alan H.} and Barbara Crain and Radtke, {Rodney A.}",

year = "1993",

month = dec,

doi = "10.1148/radiology.189.3.8234712",

language = "English (US)",

volume = "189",

pages = "835--842",

journal = "RADIOLOGY",

issn = "0033-8419",

publisher = "Radiological Society of North America Inc.",

number = "3",

}

TY - JOUR

T1 - Complex partial seizures and mesial temporal sclerosis

T2 - Evaluation with fast spin-echo MR imaging

AU - Tien, Robert D.

AU - Felsberg, Gary J.

AU - De Castro, Claudio Campi

AU - Osumi, Alan K.

AU - Lewis, Darrell V.

AU - Friedman, Alan H.

AU - Crain, Barbara

AU - Radtke, Rodney A.

PY - 1993/12

Y1 - 1993/12

N2 - PURPOSE: This study was performed to determine the sensitivity and specificity of fast spin-echo (FSE) magnetic resonance (MR) imaging in detecting mesial temporal sclerosis. MATERIALS AND METHODS: Twenty-one patients with a diagnosis of complex partial seizures were studied. Criteria for abnormality included visual detection of hippocampal MR signal abnormality and atrophy or significantly decreased hippocampal volume determined by using MR morphometric techniques. RESULTS: The overall sensitivity and specificity of MR imaging in demonstrating correct lateralization of seizure focus were both 100%. The positive predictive value of FSE MR imaging was 100%. The negative predictive value was 50%. CONCLUSION: The authors recommend FSE MR imaging of the hippocampus as the imaging technique of choice in the evaluation of patients with complex partial seizures for mesial temporal sclerosis.

AB - PURPOSE: This study was performed to determine the sensitivity and specificity of fast spin-echo (FSE) magnetic resonance (MR) imaging in detecting mesial temporal sclerosis. MATERIALS AND METHODS: Twenty-one patients with a diagnosis of complex partial seizures were studied. Criteria for abnormality included visual detection of hippocampal MR signal abnormality and atrophy or significantly decreased hippocampal volume determined by using MR morphometric techniques. RESULTS: The overall sensitivity and specificity of MR imaging in demonstrating correct lateralization of seizure focus were both 100%. The positive predictive value of FSE MR imaging was 100%. The negative predictive value was 50%. CONCLUSION: The authors recommend FSE MR imaging of the hippocampus as the imaging technique of choice in the evaluation of patients with complex partial seizures for mesial temporal sclerosis.

KW - Brain, abnormalities, 1341.142, 1341.83

KW - Epilepsy

KW - Magnetic resonance (MR), thin-section, 1341.121411, 1341.121416

UR - http://www.scopus.com/inward/record.url?scp=0027430891&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027430891&partnerID=8YFLogxK

U2 - 10.1148/radiology.189.3.8234712

DO - 10.1148/radiology.189.3.8234712

M3 - Article

C2 - 8234712

AN - SCOPUS:0027430891

SN - 0033-8419

VL - 189

SP - 835

EP - 842

JO - RADIOLOGY

JF - RADIOLOGY

IS - 3

ER -

Complex partial seizures and mesial temporal sclerosis: Evaluation with fast spin-echo MR imaging

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this