Complement as a mediator of allograft injury: An inflammatory view

William M. Baldwin, Milagros Samaniego, Zhiping Qian, Hirofumi Ota, Barbara A. Wasowska, Fred Sanfilippo, Ralph H. Hruban

Research output: Contribution to journalArticle

Abstract

Complement regulates many of the mediators of inflammation, immunity, and repair. As a result, complement is an important link between antigen-independent and antigen-dependent immune responses to transplanted organs. This review discusses the role of complement in activating platelets, granulocytes, monocytes, macrophages, lymphocytes, endothelial cells, and vascular smooth muscle cells at different stages after organ transplantation.

Original languageEnglish (US)
Pages (from-to)41-51
Number of pages11
JournalTransplantation Reviews
Volume14
Issue number1
DOIs
StatePublished - Jan 2000

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ASJC Scopus subject areas

  • Transplantation

Cite this

Baldwin, W. M., Samaniego, M., Qian, Z., Ota, H., Wasowska, B. A., Sanfilippo, F., & Hruban, R. H. (2000). Complement as a mediator of allograft injury: An inflammatory view. Transplantation Reviews, 14(1), 41-51. https://doi.org/10.1016/S0955-470X(00)80009-9