Complement as a mediator of allograft injury: An inflammatory view

William M. Baldwin, Milagros Samaniego, Zhiping Qian, Hirofumi Ota, Barbara A. Wasowska, Fred Sanfilippo, Ralph H. Hruban

Research output: Contribution to journalArticlepeer-review


Complement regulates many of the mediators of inflammation, immunity, and repair. As a result, complement is an important link between antigen-independent and antigen-dependent immune responses to transplanted organs. This review discusses the role of complement in activating platelets, granulocytes, monocytes, macrophages, lymphocytes, endothelial cells, and vascular smooth muscle cells at different stages after organ transplantation.

Original languageEnglish (US)
Pages (from-to)41-51
Number of pages11
JournalTransplantation Reviews
Issue number1
StatePublished - Jan 2000

ASJC Scopus subject areas

  • Transplantation


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