Compensation of nonlinear distortions in photon-counting spectral CT: Deadtime loss, spectral response, and beam hardening effects

J. Cammin, S. Srivastava, Q. Tang, W. C. Barber, J. S. Iwanczyk, N. E. Hartsough, K. Taguchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Photon counting detectors are an emerging technology for spectral computed tomography. They have the potential to improve tissue contrast and specificity, reduce dose, and enable novel applications for K-edge and functional imaging. In this presentation various non-linear distortions were investigated that affect the image quality in photon-counting spectral CT: deadtime losses and spectral response, inherent to the new technology, and beam hardening artifacts that stem from the use of a polychromatic x-ray source. These effects were corrected or compensated for by performing calibration measurements. Techniques from material decomposition were applied to reconstruct images at a desired energy. Two methods were compared to synthesize a single monoenergetic image from photon counting data with multiple energy bins. The parameters were optimized to maximize a given image quality index. The procedures were evaluated on phantom data acquired on an experimental CT scanner with photon-counting detectors with two energy thresholds.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2012
Subtitle of host publicationPhysics of Medical Imaging
StatePublished - May 4 2012
EventMedical Imaging 2012: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 5 2012Feb 8 2012

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherMedical Imaging 2012: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA


  • beam hardening
  • deadtime losses
  • energy-resolved computed tomography
  • material decomposition
  • photon-counting detectors
  • pulse-pileup
  • spectral CT
  • spectral response

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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