Compartmentalized microfluidic platform integrated with subcellular electrical stimulation for studying activity-dependent axon myelination

Agata Blasiak, Hae Ung Lee, Sudip Nag, In Hong Yang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Myelination is governed by a neuron/glia interaction - whole neuron electrical stimulation enhances myelination. We integrated a compartmentalized microfluidic platform with electrical stimulation and demonstrated that subcellular activity input is sufficient to induce activity-dependent myelination.

Original languageEnglish (US)
Title of host publication2016 International Conference on Optical MEMS and Nanophotonics, OMN 2016 - Proceedings
PublisherIEEE Computer Society
Volume2016-September
ISBN (Electronic)9781509010356
DOIs
StatePublished - Sep 13 2016
Event21st International Conference on Optical MEMS and Nanophotonics, OMN 2016 - Singapore, Singapore
Duration: Jul 31 2016Aug 4 2016

Other

Other21st International Conference on Optical MEMS and Nanophotonics, OMN 2016
CountrySingapore
CitySingapore
Period7/31/168/4/16

Keywords

  • electrical stimulation
  • glia
  • microfluidics
  • myelination
  • sensory neurons

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

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