Abstract
Background and Purpose: Use of rabbits in orthopedic investigations is common. In this study, focus is on factors that influence bone healing and on distraction osteogenesis. Biomechanical characteristics of two external fixator systems (Orthofix device and Hoffmann device) for long bones were tested. Methods: Twelve freshly dissected tibiae were obtained from six skeletally mature New Zealand White rabbits, and four-point bending stiffness in two planes (90 and 180°to the fixator pins) and torsional stiffness and strength of the bone-fixator complex were evaluated by use of a material testing machine. Results: In four-point bending, Orthofix device had higher stiffness and strength, compared with Hoffmann device. When the load was applied 180°to the pins, both devices had higher stiffness, compared with that at 90°. In torsional testing, Orthofix device had significantly higher stiffness and strength. Conclusions: Significant differences in structural properties between the two systems were evident. Loading direction and gap conditions were important factors in determining properties of the systems. Therefore, type of external fixation system and fixation technique should be considered when designing experiments, using the rabbit long bone model.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 650-654 |
| Number of pages | 5 |
| Journal | Laboratory Animal Science |
| Volume | 49 |
| Issue number | 6 |
| State | Published - 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
Cite this
Comparison of two systems for tibial external fixation in rabbits. / Meffert, Rainer H.; Tis, John E; Lounici, Smain; Rogers, Jonathan S.; Inoue, Nozomu; Chao, Edmund Y S.
In: Laboratory Animal Science, Vol. 49, No. 6, 1999, p. 650-654.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of two systems for tibial external fixation in rabbits
AU - Meffert, Rainer H.
AU - Tis, John E
AU - Lounici, Smain
AU - Rogers, Jonathan S.
AU - Inoue, Nozomu
AU - Chao, Edmund Y S
PY - 1999
Y1 - 1999
N2 - Background and Purpose: Use of rabbits in orthopedic investigations is common. In this study, focus is on factors that influence bone healing and on distraction osteogenesis. Biomechanical characteristics of two external fixator systems (Orthofix device and Hoffmann device) for long bones were tested. Methods: Twelve freshly dissected tibiae were obtained from six skeletally mature New Zealand White rabbits, and four-point bending stiffness in two planes (90 and 180°to the fixator pins) and torsional stiffness and strength of the bone-fixator complex were evaluated by use of a material testing machine. Results: In four-point bending, Orthofix device had higher stiffness and strength, compared with Hoffmann device. When the load was applied 180°to the pins, both devices had higher stiffness, compared with that at 90°. In torsional testing, Orthofix device had significantly higher stiffness and strength. Conclusions: Significant differences in structural properties between the two systems were evident. Loading direction and gap conditions were important factors in determining properties of the systems. Therefore, type of external fixation system and fixation technique should be considered when designing experiments, using the rabbit long bone model.
AB - Background and Purpose: Use of rabbits in orthopedic investigations is common. In this study, focus is on factors that influence bone healing and on distraction osteogenesis. Biomechanical characteristics of two external fixator systems (Orthofix device and Hoffmann device) for long bones were tested. Methods: Twelve freshly dissected tibiae were obtained from six skeletally mature New Zealand White rabbits, and four-point bending stiffness in two planes (90 and 180°to the fixator pins) and torsional stiffness and strength of the bone-fixator complex were evaluated by use of a material testing machine. Results: In four-point bending, Orthofix device had higher stiffness and strength, compared with Hoffmann device. When the load was applied 180°to the pins, both devices had higher stiffness, compared with that at 90°. In torsional testing, Orthofix device had significantly higher stiffness and strength. Conclusions: Significant differences in structural properties between the two systems were evident. Loading direction and gap conditions were important factors in determining properties of the systems. Therefore, type of external fixation system and fixation technique should be considered when designing experiments, using the rabbit long bone model.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033452038&partnerID=8YFLogxK
M3 - Article
C2 - 10638502
AN - SCOPUS:0033452038
VL - 49
SP - 650
EP - 654
JO - Comparative Medicine
JF - Comparative Medicine
SN - 1532-0820
IS - 6
ER -